Double-Stranded RNA Viral Infection in Tehran Trichomonas Vaginalis Isolates

Background: Trichomonas vaginalis is a pathogenic protozoon and may be contaminated with dsRNA virus called Trichomonas vaginalis virus (TVV). The viral infection is an important factor for its pathogene­sis and sensitivity to metronidazole. The presence of TVV is associated with qualitative and qua...

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Bibliographic Details
Published in:Iranian journal of parasitology 2013-03, Vol.8 (1), p.60-64
Main Authors: A Haghighi, SJ Seyyed –Tabaee, Z Valadkhani, M Bandehpour, S Heidary, AR Abadi, B Kazemi
Format: Article
Language:English
Subjects:
dsRNA Virus
Trichomonas Vaginalis
Viral Infection
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Summary:Background: Trichomonas vaginalis is a pathogenic protozoon and may be contaminated with dsRNA virus called Trichomonas vaginalis virus (TVV). The viral infection is an important factor for its pathogene­sis and sensitivity to metronidazole. The presence of TVV is associated with qualitative and quantitative expression of cysteine proteinases and surface immunogenic; P270. The purpose of this study was to determine TVV frequency in T. vaginalis clinical isolates in Tehran, Iran.Methods: The 46 T. vaginalis isolates were collected from Tehran Province and cultured in TYI-S-33 culture medium. Viral RNA was extracted and RT-PCR was done.Results: Of 46 T. vaginalis isolates, 8 isolates (17.39%) were infected with TVV-1. There was not any association between patient age and TVV- infected T. vaginalis. There were 17.39% viral infection in T. vaginalis isolates which was lower than that reported by other researchers.Conclusion: This is the first report on T. vaginalis isolates infection by TVV-1 in Iran.
ISSN:1735-7020
2008-238X