Unusual Extra-Axial and Extracranial Recurrence in an IDH Mutant Astrocytoma: A Case Report

Isocitrate dehydrogenase mutant gliomas generally have a better prognosis than their wild-type counterpart. Recurrences are generally within the radiation field in the primary tumoral bed. Remote recurrence is uncommon and is usually intraparenchymal. Transformation to a higher grade has been observ...

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Bibliographic Details
Published in:The Indian journal of radiology & imaging 2024-04, Vol.34 (2), p.351-355
Main Authors: Nair, Swetha M, Sahu, Arpita, Prasad, Apurva, George, Asha Mary, Goel, Atul, Gupta, Tejpal
Format: Article
Language:English
Subjects:
astrocytoma
Case Report
extra-axial
extracranial
glioma
IDH mutant
metastases
recurrence
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Summary:Isocitrate dehydrogenase mutant gliomas generally have a better prognosis than their wild-type counterpart. Recurrences are generally within the radiation field in the primary tumoral bed. Remote recurrence is uncommon and is usually intraparenchymal. Transformation to a higher grade has been observed with TP53 mutants. Presentation of glioma as an extra-axial lesion is extremely uncommon. No such cases of remote intracranial extra-axial recurrence have been reported in the literature. We describe the unique imaging findings in this case and attempt to formulate possible diagnoses. Intraoperative and pathological findings confirmed this unusual recurrence pattern.
ISSN:0971-3026
1998-3808
DOI:10.1055/s-0043-1777012