Efficacy and safety of acupuncture therapy for Parkinson’s disease with neuropsychiatric symptoms: protocol for a systematic review and meta-analysis

IntroductionNeuropsychiatric symptoms (NPS) are common non-motor symptoms among patients with Parkinson’s disease (PD) and significantly impact their overall quality of life detrimentally. Several studies have reported the clinical effect of acupuncture therapy in treating NPS in PD. Therefore, the...

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Bibliographic Details
Published in:BMJ open 2024-05, Vol.14 (5), p.e081041
Main Authors: Tan, Weiqiang, Liu, Qing, Cen, Mingjun, Leong, Ian I, Pan, Zhaoquan, Liao, Muxi, Zhuang, Lixing
Format: Article
Language:English
Subjects:
Acupuncture
Acupuncture Therapy - methods
Adult psychiatry
Antipsychotics
Anxiety
Apathy
Bias
Chinese medicine
Citation indexes
Clinical trials
Cognitive ability
Disease
Drug dosages
Electroacupuncture
Humans
Medical research
Meta-analysis
Meta-Analysis as Topic
Movement disorders
Neurology
Parkinson Disease - complications
Parkinson Disease - therapy
Parkinson's disease
Psychotropic drugs
Quality of Life
Randomized Controlled Trials as Topic
Research Design
Software
Systematic review
Systematic Reviews as Topic
Treatment Outcome
Citations: Items that this one cites
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Summary:IntroductionNeuropsychiatric symptoms (NPS) are common non-motor symptoms among patients with Parkinson’s disease (PD) and significantly impact their overall quality of life detrimentally. Several studies have reported the clinical effect of acupuncture therapy in treating NPS in PD. Therefore, the objective of this systematic review is to evaluate the potential inclusion of acupuncture therapy as an integral component of complementary treatment for PD with NPS.Methods and analysisFrom their inception until 1 December 2023, we will search eight databases, including PubMed, Cochrane Library, Embase, Web of Science, China National Knowledge Infrastructure, China Science Periodical Database, Chinese Citation Database and China Biology Medicine disc for randomised controlled trials examining the effectiveness of acupuncture for PD with NPS. Literature screening and data extraction will be carried out independently by the authors. RevMan V.5.3 software will be used for meta-analysis, while the Cochrane risk-of-bias tool will assess the potential for bias.Ethics and disseminationThis systematic review protocol does not require ethical approval because it does not include private information or data of participants. This article will be published in a peer-reviewed journal.PROSPERO registration numberCRD42022324494
ISSN:2044-6055
2044-6055
DOI:10.1136/bmjopen-2023-081041