An observational study of fixed-dose Tanacetum parthenium nutraceutical preparation for prophylaxis of pediatric headache

Migraine is one of the most prevalent chronic pain manifestations of childhood. Despite the multitude of available treatments, parents are often concerned about chronic therapies and pediatricians have insufficient confidence in prescribing prophylactic drugs. Therefore, there is now growing interes...

Full description

Saved in:
Bibliographic Details
Published in:Italian journal of pediatrics 2019-03, Vol.45 (1), p.36-36, Article 36
Main Authors: Moscano, Filomena, Guiducci, Michela, Maltoni, Lucia, Striano, Pasquale, Ledda, Maria Giuseppina, Zoroddu, Francesco, Raucci, Umberto, Villa, Maria Pia, Parisi, Pasquale
Format: Article
Language:English
Subjects:
Adolescent
Analysis of Variance
Child
Children
Chronic illnesses
Chronic pain
Cohort Studies
Dietary Supplements
Female
Follow-Up Studies
Functional foods & nutraceuticals
Headache
Headaches
Holistic Health
Humans
Italy
Magnesium
Magnesium - therapeutic use
Male
Migraine
Migraine Disorders - drug therapy
Migraine Disorders - prevention & control
Neurology
Nutraceuticals
Observational studies
Observational study
Pain
Pain Measurement
Pathogenesis
Patients
Pediatric migraine
Pediatrics
Plant Extracts - therapeutic use
Plants, Medicinal
Prevention
Prophylaxis
Prospective Studies
Riboflavin
Riboflavin - therapeutic use
Risk Assessment
Severity of Illness Index
Statistics, Nonparametric
Tanacetum parthenium
Teenagers
Tension-Type Headache - drug therapy
Tension-Type Headache - prevention & control
Treatment Outcome
Ubiquinone - analogs & derivatives
Ubiquinone - therapeutic use
Vitamin B
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Migraine is one of the most prevalent chronic pain manifestations of childhood. Despite the multitude of available treatments, parents are often concerned about chronic therapies and pediatricians have insufficient confidence in prescribing prophylactic drugs. Therefore, there is now growing interest for natural supplements used to control recurrent migraine headaches. Such approach may increase acceptance and adherence to long-term prophylaxis therapy in children. This is an observational multicenter study performed in children (n = 91) with migraine, with (MO) or without aura (MA), or tension-type headache (TTH). A fixed-dose Andrographis paniculata, CoQ10, riboflavin, and magnesium, was administered for 16 weeks. Patients were evaluated at baseline (T0), at week 8 (T1) and at the end of treatment at week 16 (T2). A follow-up period occurred at week 20 (T3) and week 32 (T4). The herbal supplement significantly reduced the frequency of headaches in TTH patients during treatment period (T0: 11.97 + 1.92 vs T2: 5.13 + 1.93; p 
ISSN:1824-7288
1720-8424
1824-7288
DOI:10.1186/s13052-019-0624-z