Leptin levels in gingival crevicular fluid during orthodontic tooth movement

Aim: To evaluate the levels of leptin in gingival crevicular fluid (GCF) during orthodontic tooth movement and to find the role of leptin as a mediator for tooth movement. Materials and Methods: GCF was collected from 25 subjects and the levels of leptin in it were measured. Sample (A) pretreatment,...

Full description

Saved in:
Bibliographic Details
Published in:Journal of pharmacy & bioallied science 2021-11, Vol.13 (6), p.1174-1177
Main Authors: Alaguselvaraj, Joseph, Selvaraj, Kandanraj, Bhaskaran, Porselvi, Chidambaram, Sainath, Rajasekaran, Thanigainathan, Mani, Muralimani
Format: Article
Language:English
Subjects:
cytokines
gingival crevicular fluid
Leptin
niti coil springs
Original
Orthodontics
Statistical analysis
Teeth
Citations: Items that this one cites
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Aim: To evaluate the levels of leptin in gingival crevicular fluid (GCF) during orthodontic tooth movement and to find the role of leptin as a mediator for tooth movement. Materials and Methods: GCF was collected from 25 subjects and the levels of leptin in it were measured. Sample (A) pretreatment, (B) 6 h after applying retractive orthodontic force from right side canine, (C) without retractive force from left side canine, and after 21 days from right canine (D), and left canine (E). Results: GCF Leptin concentration in pretreatment, 6 h control and 21st day control were all similar. GCF leptin concentration at 6 h test tooth site was increased which was statistically significant. GCF leptin concentration in 21st day test tooth was decreased only a little than the control tooth which shows statistically no difference. Conclusion: Leptin is one of the mediators of orthodontic tooth movement.
ISSN:0975-7406
0976-4879
0975-7406
DOI:10.4103/jpbs.jpbs_285_21