Risk factors of local recurrence following implant-based breast reconstruction in breast cancer patients

The number of patients desiring implant-based breast reconstruction has been increasing. While local recurrence is observed in patients with breast reconstruction, only a few reports have focused on the risk factors for local recurrence and the prognosis after developing local recurrence. We analyze...

Full description

Saved in:
Bibliographic Details
Published in:BMC women's health 2021-04, Vol.21 (1), p.147-12, Article 147
Main Authors: Fujihara, Miwa, Yamasaki, Rie, Ito, Mitsuya, Shien, Tadahiko, Maeda, Reina, Kin, Takanori, Ueno, Ayako, Kajiwara, Yukiko, Kawasaki, Kensuke, Ichimura, Kouichi, Mihara, Hiroya, Kimura, Naritaka, Ohtani, Shoichiro
Format: Article
Language:English
Subjects:
Biopsy
Breast cancer
Breast Neoplasms - surgery
Cancer
Cancer therapies
Care and treatment
Chemotherapy
Follow-Up Studies
Histology
Hospitals
Humans
Immediate breast reconstruction
Implant-based breast reconstruction
Lesions
Local recurrence
Lymphatic system
Mammaplasty
Mastectomy
Medical prognosis
Metastasis
Multivariate analysis
Neoplasm Recurrence, Local - epidemiology
Patients
Prognosis
Radiation therapy
Relapse
Retrospective Studies
Risk Factors
Surgery
Womens health
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:The number of patients desiring implant-based breast reconstruction has been increasing. While local recurrence is observed in patients with breast reconstruction, only a few reports have focused on the risk factors for local recurrence and the prognosis after developing local recurrence. We analyzed 387 patients who underwent implant-based breast reconstruction during the period from 2004 to 2017 in Hiroshima City Hospital. We retrospectively examined the risk factors for local recurrence and the outcomes of patients developing such recurrence after implant-based breast reconstruction. The median follow-up time was 59 months. The local recurrence rate was 3.1% (n = 12). The most common reason for detecting local recurrence was a palpable mass. Four patients with local recurrence had recurrence involving the skin just above the primary lesion and needle biopsy tract. All patients with local recurrence received surgery and systemic therapy and most patients received radiation therapy, all have remained free of new recurrence to date. Multivariate analysis showed lymphatic vessel invasion (HR, 6.63; 95% CI, 1.40-31.36; p = 0.017) and positive or 
ISSN:1472-6874
1472-6874
DOI:10.1186/s12905-021-01287-4