The seroprevalence trend of Helicobacter pylori infection in Gombe, Nigeria: A 5-year retrospective study

Background: Helicobacter pylori (H. pylori) infection is highly prevalent globally and half of the world’s population are carrying the pathogen with infection rates higher in low and middle-income countries. The study aim was to retrospectively determine the seroprevalence trend of H. pylori infecti...

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Bibliographic Details
Published in:Microbes and Infectious Diseases 2022-10, Vol.3 (4), p.1016-1025
Main Authors: Yakubu Ibrahim, Lateef Famoriyo, Fatima Sani, Nurul Iftida Basri, Amilia Afzan Mohd, Muhammad Abdurrahman, Idris Abdullahi
Format: Article
Language:English
Subjects:
helicobacter pylori
hygiene
nigeria
prevalence
retrospective studies
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Summary:Background: Helicobacter pylori (H. pylori) infection is highly prevalent globally and half of the world’s population are carrying the pathogen with infection rates higher in low and middle-income countries. The study aim was to retrospectively determine the seroprevalence trend of H. pylori infection among patients suspected to have dyspepsia and identify socio-demographic determinants for H. pylori seropositivity. Methods: This retrospective study was conducted at the State Specialist Hospital, Gombe, Nigeria from January 2015 to December 2019. A total of 11,935 patients were included in the study and lateral flow immunochromatographic immuno assay was used to screen for total anti H. pylori antibodies. Results: The overall sero-prevalence of H. pylori infection was 58.9%. There was significant association between H. pylori seroprevalence rate and age of subjects, (χ2=20.86; p < /em>
ISSN:2682-4132
2682-4140
DOI:10.21608/mid.2022.120290.1245