Primary versus iatrogenic (post-PCI) coronary microvascular dysfunction: a wire-based multimodal comparison

BackgroundAlthough there are studies examining each one separately, there are no data in the literature comparing the magnitudes of the iatrogenic, percutaneous coronary intervention (PCI)-induced, microvascular dysfunction (Type-4 CMD) and coronary microvascular dysfunction (CMD) in the setting of...

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Bibliographic Details
Published in:Open heart 2023-11, Vol.10 (2), p.e002437
Main Authors: Hasdemir, Hakan, Taş, Ahmet, Cevik, Erdem, Alan, Yaren, Broyd, Christopher J, Ozcan, Alp, Sonsoz, Mehmet R, Kara, Ilke, Demirtakan, Zeynep G, Parker, Kim, Perera, Divaka, Umman, Sabahattin, Sezer, Murat
Format: Article
Language:English
Subjects:
Angioplasty
Cardiovascular disease
Clinical trials
Coronary Artery Disease
Coronary vessels
Flow velocity
Hemodynamics
Iatrogenesis
Ischemia
microvascular angina
percutaneous coronary intervention
Software
Statistical analysis
Variables
Variance analysis
Vein & artery diseases
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Summary:BackgroundAlthough there are studies examining each one separately, there are no data in the literature comparing the magnitudes of the iatrogenic, percutaneous coronary intervention (PCI)-induced, microvascular dysfunction (Type-4 CMD) and coronary microvascular dysfunction (CMD) in the setting of ischaemia in non-obstructed coronary arteries (INOCA) (Type-1 CMD).ObjectivesWe aimed to compare the characteristics of Type-1 and Type-4 CMD subtypes using coronary haemodynamic (resistance and flow-related parameters), thermodynamic (wave energy-related parameters) and hyperemic ECG changes.MethodsCoronary flow reserve (CFR) value of
ISSN:2053-3624
2398-595X
2053-3624
DOI:10.1136/openhrt-2023-002437