Biorenewable Deep Eutectic Solvent for Selective and Scalable Conversion of Furfural into Cyclopentenone Derivatives

The development of novel synthetic routes to produce bioactive compounds starting from renewable sources has become an important research area in organic and medicinal chemistry. Here, we present a low-cost procedure for the tunable and selective conversion of biomass-produced furfural to cyclopente...

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Bibliographic Details
Published in:Molecules (Basel, Switzerland) Switzerland), 2018-07, Vol.23 (8), p.1891
Main Authors: Di Gioia, Maria Luisa, Nardi, Monica, Costanzo, Paola, De Nino, Antonio, Maiuolo, Loredana, Oliverio, Manuela, Procopio, Antonio
Format: Article
Language:English
Subjects:
Amino acids
Bioactive compounds
Biodegradability
Biodegradation
Biomass
biomass conversion
Carbohydrates
Chloride
Choline
Conversion
cyclopentenones
deep eutectic solvents
Furfural
Glycerol
Green chemistry
Organic chemistry
Solvents
Urea
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Summary:The development of novel synthetic routes to produce bioactive compounds starting from renewable sources has become an important research area in organic and medicinal chemistry. Here, we present a low-cost procedure for the tunable and selective conversion of biomass-produced furfural to cyclopentenone derivatives using a mixture of choline chloride and urea as a biorenewable deep eutectic solvent (DES). The proposed medium is a nontoxic, biodegradable, and could be reused up to four times without any unfavorable effect on the reaction yield. The process is tunable, clean, cheap, simple and scalable and meets most of the criteria; therefore, it can be considered as an environmental sustainable process in a natural reaction medium.
ISSN:1420-3049
1420-3049
DOI:10.3390/molecules23081891