Post-streptococcal reactive arthritis in children: a distinct entity from acute rheumatic fever

There is a debate whether post-streptococcal reactive arthritis (PSRA) is a separate entity or a condition on the spectrum of acute rheumatic fever (ARF). We believe that PSRA is a distinct entity and in this paper we review the substantial differences between PSRA and ARF. We show how the demograph...

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Bibliographic Details
Published in:Pediatric Rheumatology 2011-10, Vol.9 (1), p.32-32, Article 32
Main Authors: Uziel, Yosef, Perl, Liat, Barash, Judith, Hashkes, Philip J
Format: Article
Language:English
Subjects:
Antibiotics
Arthritis
Arthritis, Infectious
Case studies
Complications and side effects
Diagnosis
Drug therapy
Fever
Health aspects
Hospitals
Infectious arthritis
Pain
Pediatrics
Review
Rheumatic fever
Rheumatology
Risk factors
Viral infections
Writing
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Summary:There is a debate whether post-streptococcal reactive arthritis (PSRA) is a separate entity or a condition on the spectrum of acute rheumatic fever (ARF). We believe that PSRA is a distinct entity and in this paper we review the substantial differences between PSRA and ARF. We show how the demographic, clinical, genetic and treatment characteristics of PSRA differ from ARF. We review diagnostic criteria and regression formulas that attempt to classify patients with PSRA as opposed to ARF. The important implication of these findings may relate to the issue of prophylactic antibiotics after PSRA. However, future trials will be necessary to conclusively answer that question.
ISSN:1546-0096
1546-0096
DOI:10.1186/1546-0096-9-32