Chordal force profile after neochordal repair of anterior mitral valve prolapse: An ex vivo studyCentral MessagePerspective

Objective: This study aimed to biomechanically evaluate the force profiles on the anterior primary and secondary chordae after neochord repair for anterior valve prolapse with varied degrees of residual mitral regurgitation using an ex vivo heart simulator. Methods: The experiment used 8 healthy por...

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Bibliographic Details
Published in:JTCVS open 2023-09, Vol.15, p.164-172
Main Authors: Shin Yajima, MD, PhD, Yuanjia Zhu, MD, MS, Charles J. Stark, MS, Robert J. Wilkerson, BS, Matthew H. Park, MS, Elde Stefan, MD, Y. Joseph Woo, MD
Format: Article
Language:English
Subjects:
anterior valve prolapse
mitral valve
mitral valve prolapse
mitral valve repair
neochord repair
residual mitral regurgitation
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Summary:Objective: This study aimed to biomechanically evaluate the force profiles on the anterior primary and secondary chordae after neochord repair for anterior valve prolapse with varied degrees of residual mitral regurgitation using an ex vivo heart simulator. Methods: The experiment used 8 healthy porcine mitral valves. Chordal forces were measured using fiber Bragg grating sensors on primary and secondary chordae from A2 segments. The anterior valve prolapse model was generated by excising 2 primary chordae at the A2 segment. Neochord repair was performed with 2 pairs of neochords. Varying neochord lengths simulated postrepair residual mitral regurgitation with regurgitant fraction at >30% (moderate), 10% to 30% (mild), and
ISSN:2666-2736
2666-2736