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Evaluation of Demographic, Clinical, and Histological Characteristics of Spitz Nevus Among Iranian Patients: A Retrospective Study From 2016 to 2021
ABSTRACT Background and Aims Spitz nevus is a rare benign tumor classified among unusual melanocytic nevi. This study aimed to identify the demographic, clinical, and histopathological characteristics of Spitz nevus among Iranian patients. Methods This descriptive, retrospective study involved revie...
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| Published in: | Health science reports 2024-12, Vol.7 (12), p.e70274-n/a |
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| creator | Aryanian, Zeinab Kamyab, Kambiz Shakoei, Safoura Etesami, Ifa Azhari, Vahidehsadat Hesami, Sami Khayyat, Azadeh Hatami, Parvaneh |
| description | ABSTRACT
Background and Aims
Spitz nevus is a rare benign tumor classified among unusual melanocytic nevi. This study aimed to identify the demographic, clinical, and histopathological characteristics of Spitz nevus among Iranian patients.
Methods
This descriptive, retrospective study involved reviewing the records of patients diagnosed with Spitz nevus at a referral and academic hospital in Iran between 2016 and 2021. Data were extracted regarding demographic characteristics, including age, gender, location, clinical symptoms, disease duration, medical history, and medication history. Additionally, biopsied lesions were evaluated for histopathological features.
Results
A total of 86 patients were evaluated, comprising 37 males (43.5%) and 49 females (55.5%). The mean age was 15.6 years (SD ± 14.8). The most common sites of involvement were the upper extremities (23.3%) and face (17.4%). Disease durations of 1 and 2 years were the most prevalent, observed in 24 (27.9%) and 26 patients (30.2%), respectively. Notably, none of the patients had any underlying diseases. Histopathological evaluation revealed compound Spitz nevus in 25 patients (29.4%), junctional Spitz nevus in 14 patients (16.5%), and dermal Spitz nevus in 10 patients (11.8%).
Conclusion
This study provides a comprehensive overview of the demographics, clinical presentation, and histopathological features of Spitz nevus among Iranian patients, highlighting the necessity for ongoing research and innovation in diagnostic techniques. |
| doi_str_mv | 10.1002/hsr2.70274 |
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Background and Aims
Spitz nevus is a rare benign tumor classified among unusual melanocytic nevi. This study aimed to identify the demographic, clinical, and histopathological characteristics of Spitz nevus among Iranian patients.
Methods
This descriptive, retrospective study involved reviewing the records of patients diagnosed with Spitz nevus at a referral and academic hospital in Iran between 2016 and 2021. Data were extracted regarding demographic characteristics, including age, gender, location, clinical symptoms, disease duration, medical history, and medication history. Additionally, biopsied lesions were evaluated for histopathological features.
Results
A total of 86 patients were evaluated, comprising 37 males (43.5%) and 49 females (55.5%). The mean age was 15.6 years (SD ± 14.8). The most common sites of involvement were the upper extremities (23.3%) and face (17.4%). Disease durations of 1 and 2 years were the most prevalent, observed in 24 (27.9%) and 26 patients (30.2%), respectively. Notably, none of the patients had any underlying diseases. Histopathological evaluation revealed compound Spitz nevus in 25 patients (29.4%), junctional Spitz nevus in 14 patients (16.5%), and dermal Spitz nevus in 10 patients (11.8%).
Conclusion
This study provides a comprehensive overview of the demographics, clinical presentation, and histopathological features of Spitz nevus among Iranian patients, highlighting the necessity for ongoing research and innovation in diagnostic techniques.</description><identifier>ISSN: 2398-8835</identifier><identifier>EISSN: 2398-8835</identifier><identifier>DOI: 10.1002/hsr2.70274</identifier><identifier>PMID: 39703492</identifier><language>eng</language><publisher>United States: John Wiley & Sons, Inc</publisher><subject>Age ; Biopsy ; clinical ; demographics ; Disease ; Gender ; Histopathology ; Hospitals ; Hypotheses ; Illnesses ; Melanoma ; Original Research ; Pathology ; Patients ; Skin cancer ; Spitz nevus ; Tumors ; Variables</subject><ispartof>Health science reports, 2024-12, Vol.7 (12), p.e70274-n/a</ispartof><rights>2024 The Author(s). published by Wiley Periodicals LLC.</rights><rights>2024 The Author(s). Health Science Reports published by Wiley Periodicals LLC.</rights><rights>2024. This work is published under http://creativecommons.org/licenses/by-nc-nd/4.0/ (the "License"). Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License.</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><cites>FETCH-LOGICAL-c4044-64263696667bff5f89fb45f6d98841c1bc3a91c0565b2e00636688450cc557973</cites><orcidid>0000-0001-6790-7633 ; 0009-0001-2318-7117 ; 0000-0002-3531-2907</orcidid></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.proquest.com/docview/3150044154/fulltextPDF?pq-origsite=primo$$EPDF$$P50$$Gproquest$$Hfree_for_read</linktopdf><linktohtml>$$Uhttps://www.proquest.com/docview/3150044154?pq-origsite=primo$$EHTML$$P50$$Gproquest$$Hfree_for_read</linktohtml><link.rule.ids>230,314,724,777,781,882,11543,25734,27905,27906,36993,36994,44571,46033,46457,53772,53774,74875</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/39703492$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Aryanian, Zeinab</creatorcontrib><creatorcontrib>Kamyab, Kambiz</creatorcontrib><creatorcontrib>Shakoei, Safoura</creatorcontrib><creatorcontrib>Etesami, Ifa</creatorcontrib><creatorcontrib>Azhari, Vahidehsadat</creatorcontrib><creatorcontrib>Hesami, Sami</creatorcontrib><creatorcontrib>Khayyat, Azadeh</creatorcontrib><creatorcontrib>Hatami, Parvaneh</creatorcontrib><title>Evaluation of Demographic, Clinical, and Histological Characteristics of Spitz Nevus Among Iranian Patients: A Retrospective Study From 2016 to 2021</title><title>Health science reports</title><addtitle>Health Sci Rep</addtitle><description>ABSTRACT
Background and Aims
Spitz nevus is a rare benign tumor classified among unusual melanocytic nevi. This study aimed to identify the demographic, clinical, and histopathological characteristics of Spitz nevus among Iranian patients.
Methods
This descriptive, retrospective study involved reviewing the records of patients diagnosed with Spitz nevus at a referral and academic hospital in Iran between 2016 and 2021. Data were extracted regarding demographic characteristics, including age, gender, location, clinical symptoms, disease duration, medical history, and medication history. Additionally, biopsied lesions were evaluated for histopathological features.
Results
A total of 86 patients were evaluated, comprising 37 males (43.5%) and 49 females (55.5%). The mean age was 15.6 years (SD ± 14.8). The most common sites of involvement were the upper extremities (23.3%) and face (17.4%). Disease durations of 1 and 2 years were the most prevalent, observed in 24 (27.9%) and 26 patients (30.2%), respectively. Notably, none of the patients had any underlying diseases. Histopathological evaluation revealed compound Spitz nevus in 25 patients (29.4%), junctional Spitz nevus in 14 patients (16.5%), and dermal Spitz nevus in 10 patients (11.8%).
Conclusion
This study provides a comprehensive overview of the demographics, clinical presentation, and histopathological features of Spitz nevus among Iranian patients, highlighting the necessity for ongoing research and innovation in diagnostic techniques.</description><subject>Age</subject><subject>Biopsy</subject><subject>clinical</subject><subject>demographics</subject><subject>Disease</subject><subject>Gender</subject><subject>Histopathology</subject><subject>Hospitals</subject><subject>Hypotheses</subject><subject>Illnesses</subject><subject>Melanoma</subject><subject>Original Research</subject><subject>Pathology</subject><subject>Patients</subject><subject>Skin cancer</subject><subject>Spitz nevus</subject><subject>Tumors</subject><subject>Variables</subject><issn>2398-8835</issn><issn>2398-8835</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2024</creationdate><recordtype>article</recordtype><sourceid>24P</sourceid><sourceid>PIMPY</sourceid><sourceid>DOA</sourceid><recordid>eNp9ks1u1DAQgCMEolXphQdAlrgg1C3-j80FrZaWXakC1IWz5ThO1qskDnayaHmOPnC9TalaDpzGmvn8aWY0WfYawXMEIf6wiQGf5xDn9Fl2jIkUMyEIe_7ofZSdxriFCYaYMiFfZkdE5pBQiY-zm4udbkY9ON8BX4HPtvV10P3GmTOwaFznjG7OgO5KsHRx8I2vDxmw2OigzWBDSjoTD1_XvRv-gK92N0Ywb31Xg1XQndMd-J70thviRzAH13YIPvbWDG5nwXoYyz24DL4FGCIOBp8iRq-yF5Vuoj29jyfZz8uLH4vl7Orbl9VifjUzFFI64xRzwiXnPC-qilVCVgVlFS-lEBQZVBiiJTKQcVZgC2GCeaowaAxjuczJSbaavKXXW9UH1-qwV147dZfwoVY6pPkaqyxHlrMy19wyaqpcGsIKqZEgSSxFlVyfJlc_Fq0tTRo46OaJ9GmlcxtV-51CiDMmEUmGd_eG4H-NNg6qddHYptGd9WNUBNGcCoqJSOjbf9CtH0OXdpUoBtNyEKOJej9RJq08Bls9dIOgOhyPOhyPujueBL953P8D-vdUEoAm4Ldr7P4_KrVcX-NJegvTEc0V</recordid><startdate>202412</startdate><enddate>202412</enddate><creator>Aryanian, Zeinab</creator><creator>Kamyab, Kambiz</creator><creator>Shakoei, Safoura</creator><creator>Etesami, Ifa</creator><creator>Azhari, Vahidehsadat</creator><creator>Hesami, Sami</creator><creator>Khayyat, Azadeh</creator><creator>Hatami, Parvaneh</creator><general>John Wiley & Sons, Inc</general><general>John Wiley and Sons Inc</general><general>Wiley</general><scope>24P</scope><scope>WIN</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>3V.</scope><scope>7X7</scope><scope>7XB</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>AZQEC</scope><scope>BENPR</scope><scope>CCPQU</scope><scope>DWQXO</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>K9.</scope><scope>M0S</scope><scope>PIMPY</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>PRINS</scope><scope>7X8</scope><scope>5PM</scope><scope>DOA</scope><orcidid>https://orcid.org/0000-0001-6790-7633</orcidid><orcidid>https://orcid.org/0009-0001-2318-7117</orcidid><orcidid>https://orcid.org/0000-0002-3531-2907</orcidid></search><sort><creationdate>202412</creationdate><title>Evaluation of Demographic, Clinical, and Histological Characteristics of Spitz Nevus Among Iranian Patients: A Retrospective Study From 2016 to 2021</title><author>Aryanian, Zeinab ; Kamyab, Kambiz ; Shakoei, Safoura ; Etesami, Ifa ; Azhari, Vahidehsadat ; Hesami, Sami ; Khayyat, Azadeh ; Hatami, Parvaneh</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c4044-64263696667bff5f89fb45f6d98841c1bc3a91c0565b2e00636688450cc557973</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2024</creationdate><topic>Age</topic><topic>Biopsy</topic><topic>clinical</topic><topic>demographics</topic><topic>Disease</topic><topic>Gender</topic><topic>Histopathology</topic><topic>Hospitals</topic><topic>Hypotheses</topic><topic>Illnesses</topic><topic>Melanoma</topic><topic>Original Research</topic><topic>Pathology</topic><topic>Patients</topic><topic>Skin cancer</topic><topic>Spitz nevus</topic><topic>Tumors</topic><topic>Variables</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Aryanian, Zeinab</creatorcontrib><creatorcontrib>Kamyab, Kambiz</creatorcontrib><creatorcontrib>Shakoei, Safoura</creatorcontrib><creatorcontrib>Etesami, Ifa</creatorcontrib><creatorcontrib>Azhari, Vahidehsadat</creatorcontrib><creatorcontrib>Hesami, Sami</creatorcontrib><creatorcontrib>Khayyat, Azadeh</creatorcontrib><creatorcontrib>Hatami, Parvaneh</creatorcontrib><collection>Wiley Online Library Open Access</collection><collection>Wiley Online Library Free Content</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>ProQuest Central (Corporate)</collection><collection>Health & Medical Collection</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>Hospital Premium Collection</collection><collection>Hospital Premium Collection (Alumni Edition)</collection><collection>ProQuest Central (Alumni) (purchase pre-March 2016)</collection><collection>ProQuest Central (Alumni)</collection><collection>ProQuest Central</collection><collection>ProQuest Central Essentials</collection><collection>AUTh Library subscriptions: ProQuest Central</collection><collection>ProQuest One Community College</collection><collection>ProQuest Central Korea</collection><collection>Health Research Premium Collection</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>Health & Medical Collection (Alumni Edition)</collection><collection>Publicly Available Content Database</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>ProQuest Central China</collection><collection>MEDLINE - Academic</collection><collection>PubMed Central (Full Participant titles)</collection><collection>Open Access: DOAJ - Directory of Open Access Journals</collection><jtitle>Health science reports</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Aryanian, Zeinab</au><au>Kamyab, Kambiz</au><au>Shakoei, Safoura</au><au>Etesami, Ifa</au><au>Azhari, Vahidehsadat</au><au>Hesami, Sami</au><au>Khayyat, Azadeh</au><au>Hatami, Parvaneh</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Evaluation of Demographic, Clinical, and Histological Characteristics of Spitz Nevus Among Iranian Patients: A Retrospective Study From 2016 to 2021</atitle><jtitle>Health science reports</jtitle><addtitle>Health Sci Rep</addtitle><date>2024-12</date><risdate>2024</risdate><volume>7</volume><issue>12</issue><spage>e70274</spage><epage>n/a</epage><pages>e70274-n/a</pages><issn>2398-8835</issn><eissn>2398-8835</eissn><abstract>ABSTRACT
Background and Aims
Spitz nevus is a rare benign tumor classified among unusual melanocytic nevi. This study aimed to identify the demographic, clinical, and histopathological characteristics of Spitz nevus among Iranian patients.
Methods
This descriptive, retrospective study involved reviewing the records of patients diagnosed with Spitz nevus at a referral and academic hospital in Iran between 2016 and 2021. Data were extracted regarding demographic characteristics, including age, gender, location, clinical symptoms, disease duration, medical history, and medication history. Additionally, biopsied lesions were evaluated for histopathological features.
Results
A total of 86 patients were evaluated, comprising 37 males (43.5%) and 49 females (55.5%). The mean age was 15.6 years (SD ± 14.8). The most common sites of involvement were the upper extremities (23.3%) and face (17.4%). Disease durations of 1 and 2 years were the most prevalent, observed in 24 (27.9%) and 26 patients (30.2%), respectively. Notably, none of the patients had any underlying diseases. Histopathological evaluation revealed compound Spitz nevus in 25 patients (29.4%), junctional Spitz nevus in 14 patients (16.5%), and dermal Spitz nevus in 10 patients (11.8%).
Conclusion
This study provides a comprehensive overview of the demographics, clinical presentation, and histopathological features of Spitz nevus among Iranian patients, highlighting the necessity for ongoing research and innovation in diagnostic techniques.</abstract><cop>United States</cop><pub>John Wiley & Sons, Inc</pub><pmid>39703492</pmid><doi>10.1002/hsr2.70274</doi><tpages>6</tpages><orcidid>https://orcid.org/0000-0001-6790-7633</orcidid><orcidid>https://orcid.org/0009-0001-2318-7117</orcidid><orcidid>https://orcid.org/0000-0002-3531-2907</orcidid><oa>free_for_read</oa></addata></record> |
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| subjects | Age Biopsy clinical demographics Disease Gender Histopathology Hospitals Hypotheses Illnesses Melanoma Original Research Pathology Patients Skin cancer Spitz nevus Tumors Variables |
| title | Evaluation of Demographic, Clinical, and Histological Characteristics of Spitz Nevus Among Iranian Patients: A Retrospective Study From 2016 to 2021 |
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