Low vitamin D levels are associated with cognitive impairment in patients with Hashimoto thyroiditis

Cognitive impairment is commonly observed in patients with Hashimoto thyroiditis (HT). Low levels of vitamin D have been correlated with cognitive impairment in non-HT population. We examined the association of vitamin D levels with cognitive impairment in patients with HT. We recruited 194 patients...

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Bibliographic Details
Published in:BMC endocrine disorders 2018-11, Vol.18 (1), p.87-87, Article 87
Main Authors: Xu, Jun, Zhu, Xiang-Yun, Sun, Hui, Xu, Xiao-Qin, Xu, Song-Ao, Suo, Yuan, Cao, Li-Jun, Zhou, Qiang, Yu, Hui-Jie, Cao, Wei-Zhong
Format: Article
Language:English
Subjects:
25-Hydroxyvitamin D
Adult
Alzheimer's disease
Biomarkers - blood
Chronic illnesses
Cognition & reasoning
Cognitive ability
Cognitive disorders
Cognitive Dysfunction - blood
Cognitive Dysfunction - diagnosis
Cognitive Dysfunction - epidemiology
Cognitive impairment
Complications and side effects
Cross-Sectional Studies
Female
Hashimoto Disease - blood
Hashimoto Disease - diagnosis
Hashimoto Disease - epidemiology
Hashimoto’s thyroiditis
Humans
Immunoglobulins
Inflammation
Laboratories
Male
Middle Aged
Montreal cognitive assessment
Multivariate analysis
Oxidative stress
Pathogenesis
Physiological aspects
Psychological aspects
Regression analysis
Risk factors
Thyroid diseases
Thyroiditis
Vitamin
Vitamin D
Vitamin D - analogs & derivatives
Vitamin D - blood
Vitamin D Deficiency - blood
Vitamin D Deficiency - diagnosis
Vitamin D Deficiency - epidemiology
Vitamin deficiency
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Summary:Cognitive impairment is commonly observed in patients with Hashimoto thyroiditis (HT). Low levels of vitamin D have been correlated with cognitive impairment in non-HT population. We examined the association of vitamin D levels with cognitive impairment in patients with HT. We recruited 194 patients with HT and 200 healthy volunteers. Levels of serum 25-hydroxyvitamin D (25(OH)D) were measured using a competitive protein-binding assay. Cognitive funtion was assessed using Montreal Cognitive Assessment score (MoCA). Subjects with a MoCA scores
ISSN:1472-6823
1472-6823
DOI:10.1186/s12902-018-0314-7