mSphere of Influence: the Mycobiota in Human Health and Disease

Soo Chan Lee works in the field of medical mycology. In this mSphere of Influence article, he reflects on how "Interactions between commensal fungi and the C-type lectin receptor Dectin-1 influence colitis" (Science 336:1314-1317, 2012, https://doi.org/10.1126/science.1221789) by I. D. Ili...

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Bibliographic Details
Published in:mSphere 2020-01, Vol.5 (1)
Main Author: Lee, Soo Chan
Format: Article
Language:English
Subjects:
Colitis
CX3CR1 protein
Drug resistance
Fungi
Host-Microbe Biology
Inflammatory bowel disease
Intestine
Leukocytes (mononuclear)
Microbiota
Mutation
mycobiome
mycobiota
mycology
Pancreas
pathogenic fungi
Phagocytes
Roles
Studies
Tumorigenesis
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Summary:Soo Chan Lee works in the field of medical mycology. In this mSphere of Influence article, he reflects on how "Interactions between commensal fungi and the C-type lectin receptor Dectin-1 influence colitis" (Science 336:1314-1317, 2012, https://doi.org/10.1126/science.1221789) by I. D. Iliev, V. A. Funari, K. D. Taylor, Q. Nguyen, et al., "CX3CR1 mononuclear phagocytes control immunity to intestinal fungi" (Science 359:232-236, 2018, https://doi.org/10.1126/science.aao1503) by I. Leonardi, X. Li, A. Semon, D. Li, et al., and "The fungal mycobiome promotes pancreatic oncogenesis via activation of MBL" (Nature 574:264-267, 2019, https://doi.org/10.1038/s41586-019-1608-2) by B. Aykut, S. Pushalkar, R. Chen, Q. Li, et al. made an impact on him to study medically important fungi by providing a forum to understand the roles of fungal microbiota or mycobiota in human diseases and health.
ISSN:2379-5042
2379-5042
DOI:10.1128/mSphere.00974-19