Prevalence and risk factors of myopic maculopathy: a cross-sectional study in Han and Uygur adults in Xinjiang, China

ObjectivesTo estimate the prevalence, ethnic differences and associated risk factors of myopic maculopathy in Han and Uygur adults in Xinjiang, China.Design and settingA cross-sectional study with multistage, stratified cluster sampling method was conducted in Xinjiang, China.ParticipantsA total of...

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Bibliographic Details
Published in:BMJ open 2020-11, Vol.10 (11), p.e034775-e034775
Main Authors: Chen, Ting, Ma, Jin, Shan, Guang-Liang, Pa, Lize, Ding, Lin, Pan, Li, Ke, Limujiang, Mu, Hebuli, Ya, Senjiang, Tao, Ning, Dong, Fen, Wang, Ke, Zhong, Yong
Format: Article
Language:English
Subjects:
Adult
Age
Aged
Asian Continental Ancestry Group
Atrophy
Blood pressure
Body mass index
China - epidemiology
Classification
Cross-Sectional Studies
Cultural differences
Diabetes
epidemiology
Ethnicity
Female
Higher education
Humans
Hypertension
Macular Degeneration - epidemiology
Male
Middle Aged
Ophthalmology
Population
Prevalence
public health
Questionnaires
Risk Factors
Rural areas
Statistical analysis
vetreoretinal
Visual impairment
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Summary:ObjectivesTo estimate the prevalence, ethnic differences and associated risk factors of myopic maculopathy in Han and Uygur adults in Xinjiang, China.Design and settingA cross-sectional study with multistage, stratified cluster sampling method was conducted in Xinjiang, China.ParticipantsA total of 4023 Han and Uygur participants aged 40 years and older were eligible for the study.Outcome measuresThe association between myopic maculopathy and its risk factors was screened using the generalised estimating equation (GEE) model. We also investigated whether ethnic differences exist between Han and Uygur populations affected by myopic maculopathy. Myopic maculopathy was defined in accordance with International Photographic Classification and Grading System for Myopic Maculopathy.ResultsA total of 3044 subjects (5946 eyes) were included in our study (1736 Han and 1308 Uygur individuals). The participants consisted of 1256 (41.3%) men and 1788 (58.7%) women. The average age was 52.2±9.4 years, and the mean spherical equivalent (SE) was −0.18±2.31 dioptre (D). Myopic maculopathy was detected in 198 eyes of 138 participants. The age-adjusted prevalence of myopic maculopathy reached 5.8% (95% CI 4.8 to 6.8). In the GEE model, myopic maculopathy was significantly associated with old age (per year; OR: 1.16; 95% CI 1.13 to 1.19; p
ISSN:2044-6055
2044-6055
DOI:10.1136/bmjopen-2019-034775