Cannabis sativa CBD Extract Shows Promising Antibacterial Activity against Salmonella typhimurium and S. newington

Products derived from L. have gained increased interest and popularity. As these products become common amongst the public, the health and potential therapeutic values associated with hemp have become a premier focus of research. While the psychoactive and medicinal properties of products have been...

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Bibliographic Details
Published in:Molecules (Basel, Switzerland) Switzerland), 2022-04, Vol.27 (9), p.2669
Main Authors: Gildea, Logan, Ayariga, Joseph Atia, Ajayi, Olufemi S, Xu, Junhuan, Villafane, Robert, Samuel-Foo, Michelle
Format: Article
Language:English
Subjects:
Ampicillin
Anti-Bacterial Agents - pharmacology
Anti-Bacterial Agents - therapeutic use
Antibacterial activity
Antibiotics
Bacteria
Bacterial infections
By products
Cannabidiol
Cannabidiol - pharmacology
Cannabinoids
Cannabinoids - therapeutic use
Cannabis
Cannabis sativa
Chromatography
Comparative studies
Drug resistance
Fluorescence
Fluorescence microscopy
Hemp
Marijuana
membrane disruption
Multidrug resistant organisms
novel antibacterial agents
Pathogens
Plant Extracts - pharmacology
Public health
R&D
Research & development
Salmonella
Salmonella typhimurium
Streptococcus infections
Tetrahydrocannabinol
THC
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Summary:Products derived from L. have gained increased interest and popularity. As these products become common amongst the public, the health and potential therapeutic values associated with hemp have become a premier focus of research. While the psychoactive and medicinal properties of products have been extensively highlighted in the literature, the antibacterial properties of cannabidiol (CBD) have not been explored in depth. This research serves to examine the antibacterial potential of CBD against and . . In this study, we observed bacterial response to CBD exposure through biological assays, bacterial kinetics, and fluorescence microscopy. Additionally, comparative studies between CBD and ampicillin were conducted against . and . to determine comparative efficacy. Furthermore, we observed potential resistance development of our spp. against CBD treatment.
ISSN:1420-3049
1420-3049
DOI:10.3390/molecules27092669