Pulmonary blastoma with a good prognosis: a case report and review of the literature

• Published in: Journal of international medical research 2024-06, Vol.52 (6), p.3000605241254778
• Main Authors: Liu, Qingru, Li, Fengchao, Wang, Lulu, Lv, Feng, Yin, Qianqian, Liu, Guangzhen, Chen, Wen
• Format: Article
• Language: English
• Subjects: Adult; Case Report and Case Series; Chemotherapy; Cisplatin - administration & dosage; Cisplatin - therapeutic use; Docetaxel - administration & dosage; Docetaxel - therapeutic use; Humans; Lung Neoplasms - diagnosis; Lung Neoplasms - diagnostic imaging; Lung Neoplasms - pathology; Lung Neoplasms - secondary; Lung Neoplasms - surgery; Male; Metastasis; Pneumonectomy; Positron Emission Tomography Computed Tomography; Prognosis; Pulmonary Blastoma - diagnosis; Pulmonary Blastoma - pathology; Pulmonary Blastoma - surgery; Tomography; Tomography, X-Ray Computed
• ISSN: 0300-0605; 1473-2300; 1473-2300
• DOI: 10.1177/03000605241254778

Pulmonary blastoma (PB) is a rare, highly malignant tumor prone to distant metastasis and recurrence, and the prognosis of these patients is often poor. We report a case of metastatic PB with a good prognosis with the aim of providing data to support a clinical diagnosis and treatment. In December 2015, a 43-year-old male patient was admitted to our hospital because of a cough and blood-stained sputum. Positron emission-computed tomography showed massive high-density imaging in the lower lobe of the right lung, with a maximum cross-section of 76 × 58 mm. Thoracoscopic-assisted right lower lobectomy with lymph node dissection was performed. After 1 month, computed tomography showed a high possibility of metastasis. The patient then received docetaxel and cisplatin chemotherapy for a total of six courses. After chemotherapy, enhanced computed tomography showed considerable absorption of pleural effusion, and a left lobe pulmonary nodule was not detected. The postoperative pathological diagnosis was PB, and epithelial and mesenchymal differentiation components were observed. The patient continued to visit the hospital regularly for re-examination and imaging examinations. Currently, no signs of recurrence or distant metastasis have been detected.