Transcutaneous bilirubin estimation in extremely low birth weight infants receiving phototherapy: a prospective observational study

Measurement of transcutaneous bilirubin (TcB) is a quick, reliable and painless method to guide management of hyperbilirubinemia. Studies in term and late preterm infants have found that TcB measurements from covered areas (TcB-C) during phototherapy (PHT) co-relate well with serum bilirubin levels....

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Bibliographic Details
Published in:BMC pediatrics 2018-07, Vol.18 (1), p.227-227, Article 227
Main Authors: Bhargava, Vidit, Tawfik, Daniel, Niebuhr, Bruce, Jain, Sunil K
Format: Article
Language:English
Subjects:
Age
Babies
Bilirubin - blood
Birth weight
Blood groups
Care and treatment
ELBW
Female
Health aspects
Humans
Hyperbilirubinemia
Infant, Extremely Low Birth Weight
Infant, Newborn
Infant, Premature
Infants (Premature)
Jaundice, Neonatal - blood
Jaundice, Neonatal - therapy
Kernicterus
Light therapy
Male
Monitoring, Physiologic - methods
Newborn babies
Observational studies
Pediatrics
Phototherapy
Prevention
Prospective Studies
Skin
Systematic review
Transcutaneous bilirubinometry
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Summary:Measurement of transcutaneous bilirubin (TcB) is a quick, reliable and painless method to guide management of hyperbilirubinemia. Studies in term and late preterm infants have found that TcB measurements from covered areas (TcB-C) during phototherapy (PHT) co-relate well with serum bilirubin levels. Limited data exists in extremely low birth weight (ELBW) infants. In this prospective observational study, an opaque patch was placed on the back of an ELBW infant prior to initiation of PHT. TcB-C and TcB-E (TcB from exposed area) levels were measured at birth and at 24-h intervals for 5 days. Total serum bilirubin (TSB) levels were also measured within 30 min of obtaining TcB levels. A Wilcoxon signed rank test was used for data analysis. A mixed effect model was used to adjust for repeated measurements over time. The p value
ISSN:1471-2431
1471-2431
DOI:10.1186/s12887-018-1207-7