Audiological findings in patients treated with radio- and concomitant chemotherapy for head and neck tumors

To evaluate the functionality of the auditory system in patients who underwent radiotherapy and chemotherapy treatment with cisplatin to treat head and neck tumors. Case series with planned data collection. From May 2007 to May 2008 by the Department of Otorhinolaryngology and the Department of Onco...

Full description

Saved in:
Bibliographic Details
Published in:Radiation oncology (London, England) England), 2009-11, Vol.4 (1), p.53-53, Article 53
Main Authors: Dell'Aringa, Ana Helena B, Isaac, Myrian L, Arruda, Gustavo V, Esteves, Maria Carolina B N, Dell'aringa, Alfredo Rafael, Júnior, José Luis S, Rodrigues, Alexandre F
Format: Article
Language:English
Subjects:
Aged
Antineoplastic Agents - adverse effects
Cancer
Care and treatment
Chemotherapy
Cisplatin - administration & dosage
Cisplatin - adverse effects
Combined Modality Therapy
Ear diseases
Female
Head & neck cancer
Head and Neck Neoplasms - therapy
Head and neck tumors
Health aspects
Hearing disorders
Hearing Disorders - etiology
Hearing Tests
Humans
Male
Medical treatment
Middle Aged
Oncology
Otolaryngology
Patient outcomes
Prevention
Radiation therapy
Radios
Radiotherapy
Radiotherapy - adverse effects
Radiotherapy Dosage
Review
Risk factors
Statistical analysis
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:To evaluate the functionality of the auditory system in patients who underwent radiotherapy and chemotherapy treatment with cisplatin to treat head and neck tumors. Case series with planned data collection. From May 2007 to May 2008 by the Department of Otorhinolaryngology and the Department of Oncology/Radiotherapy at Faculdade de Medicina de Marília. Audiological evaluation (Pure Tone Audiometry (air and bone conduction), Speech Audiometry, Tympanometry, Acoustic Reflex testing and Distortion Product Otoacoustic Emissions) was performed in 17 patients diagnosed with head and neck neoplasia and treated with chemotherapy, using cisplatin, and radiotherapy. 12 left ears (70.5%) and 11 right ears (64.7%) presented bilateral decreased hearing soon after the treatment for the frequency 1 kHz (mild auditory damage) and for the frequency 8 kHz (more significant auditory damage). Patients with head and neck cancer submitted to the conventional radiotherapy treatment, combined with the chemotherapy with cisplatin, presented a high incidence of decreased hearing by the end of treatment. Strong evidence was observed linking auditory alteration to the amount of radiotherapy treatment.
ISSN:1748-717X
1748-717X
DOI:10.1186/1748-717X-4-53