Investigating the role of peptides in effective therapies against cancer

Early diagnosis and effective treatment of cancer are challenging. To diagnose and treat cancer effectively and to overcome these challenges, fundamental innovations in traditional diagnosis and therapy are necessary. Peptides can be very helpful in this regard due to their potential and diversity....

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Bibliographic Details
Published in:Cancer cell international 2022-03, Vol.22 (1), p.139-139, Article 139
Main Authors: Naeimi, Reza, Bahmani, Asrin, Afshar, Saeid
Format: Article
Language:English
Subjects:
Amino acids
Apoptosis
Bioavailability
Brain cancer
Cancer
Cancer therapies
Cancer vaccines
Diagnosis
Drug resistance
Laboratories
Medical research
Nanoparticles
Peptides
Permeability
Review
Therapeutic effect
Tumors
Vaccines
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Summary:Early diagnosis and effective treatment of cancer are challenging. To diagnose and treat cancer effectively and to overcome these challenges, fundamental innovations in traditional diagnosis and therapy are necessary. Peptides can be very helpful in this regard due to their potential and diversity. To enhance the therapeutic potential of peptides, their limitations must be properly identified and their structures engineered and modified for higher efficiency. Promoting the bioavailability and stability of peptides is one of the main concerns. Peptides can also be effective in different areas of targeting, alone or with the help of other therapeutic agents. There has been a lot of research in this area, and the potential for variability of peptides will continue to improve this process. Another promising area in which peptides can help treat cancer is peptide vaccines, which are undergoing promising research, and high throughput technologies can lead to fundamental changes in this area. Peptides have been effective in almost all areas of cancer treatment, and some have even gone through clinical phases. However, many barriers need to be overcome to reach the desired point. The purpose of this review is to evaluate the mechanisms associated with peptides in the diagnosis and treatment of cancer. Therefore, related studies in this area will be discussed.
ISSN:1475-2867
1475-2867
DOI:10.1186/s12935-022-02553-7