Noninvasive Prenatal Screening Based on Second-Trimester Ultrasonographic Soft Markers in Low-Risk Pregnant Women

We aimed to assess the clinical application of noninvasive prenatal screening (NIPS) based on second-trimester ultrasonographic soft markers (USMs) in low-risk pregnant women. Data of pregnant women between April 2015 and December 2019 were retrospectively analyzed. Pregnant women [age at expected d...

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Bibliographic Details
Published in:Frontiers in genetics 2021-12, Vol.12, p.793894
Main Authors: Liu, Yunyun, Jing, Xiaosha, Xing, Lingling, Liu, Sha, Liu, Jianlong, Cheng, Jing, Deng, Cechuan, Bai, Ting, Xia, Tianyu, Wei, Xiang, Luo, Yuan, Zhou, Quanfang, Zhu, Qian, Liu, Hongqian
Format: Article
Language:English
Subjects:
aneuploidy
Genetics
noninvasive prenatal screening
positive predictive value
sex chromosome abnormality
trisomy 21 (Down syndrome)
ultrasonographic soft markers
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Summary:We aimed to assess the clinical application of noninvasive prenatal screening (NIPS) based on second-trimester ultrasonographic soft markers (USMs) in low-risk pregnant women. Data of pregnant women between April 2015 and December 2019 were retrospectively analyzed. Pregnant women [age at expected date of confinement (EDC) of
ISSN:1664-8021
1664-8021
DOI:10.3389/fgene.2021.793894