Decreased health-related quality of life in children and adolescents with autoimmune hepatitis

The objective of this study was to evaluate the health-related quality of life in children and adolescents with autoimmune hepatitis. A cross-sectional assessment with the Pediatric Quality of Life Inventory 4.0 (PedsQL 4.0) was completed for 80 patients with autoimmune hepatitis and 45 healthy cont...

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Bibliographic Details
Published in:Jornal de pediatria 2019-01, Vol.95 (1), p.87-93
Main Authors: Bozzini, Ana Beatriz, Neder, Luciana, Silva, Clovis A., Porta, Gilda
Format: Article
Language:English
Subjects:
Adolescence
Adolescent
Adolescência
Autoimmune hepatitis
Case-Control Studies
Child
Child, Preschool
Childhood
Chronic disease
Cross-Sectional Studies
Doença crônica
Female
Glucocorticoids - administration & dosage
Hepatite autoimune
Hepatitis, Autoimmune - drug therapy
Hepatitis, Autoimmune - psychology
Humans
Infância
Male
PEDIATRICS
PedsQL 4.0
Prednisone - administration & dosage
Qualidade de vida
Quality of life
Quality of Life - psychology
Remission Induction
Severity of Illness Index
Surveys and Questionnaires
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Summary:The objective of this study was to evaluate the health-related quality of life in children and adolescents with autoimmune hepatitis. A cross-sectional assessment with the Pediatric Quality of Life Inventory 4.0 (PedsQL 4.0) was completed for 80 patients with autoimmune hepatitis and 45 healthy controls. Demographic data, prednisone dose, disease remission state, disease severity, and abdominal pain were also evaluated. Based on the child self-reports, physical, emotional, school, and total scores were significantly lower in autoimmune hepatitis patients when compared with controls (p
ISSN:0021-7557
1678-4782
1678-4782
DOI:10.1016/j.jped.2017.10.013