Short-Term Effect of Cigarette Smoke on Exhaled Volatile Organic Compounds Profile Analyzed by an Electronic Nose

Breath analysis using an electronic nose (e-nose) is an innovative tool for exhaled volatile organic compound (VOC) analysis, which has shown potential in several respiratory and systemic diseases. It is still unclear whether cigarette smoking can be considered a confounder when analyzing the VOC-pr...

Full description

Saved in:
Bibliographic Details
Published in:Biosensors (Basel) 2022-07, Vol.12 (7), p.520
Main Authors: Dragonieri, Silvano, Quaranta, Vitaliano Nicola, Buonamico, Enrico, Battisti, Claudia, Ranieri, Teresa, Carratu, Pierluigi, Carpagnano, Giovanna Elisiana
Format: Article
Language:English
Subjects:
Accuracy
breath analysis
Cigarette smoke
Cigarette Smoking
Cigarettes
Communication
Discriminant analysis
Electronic Nose
Electronic noses
Exhalation
Humidity
Independent sample
Metabolism
Normal distribution
Odorants
Organic compounds
Principal components analysis
Respiratory diseases
Sample size
Sensors
Smoking
Tobacco
Tobacco Products
VOCs
Volatile Organic Compounds
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Breath analysis using an electronic nose (e-nose) is an innovative tool for exhaled volatile organic compound (VOC) analysis, which has shown potential in several respiratory and systemic diseases. It is still unclear whether cigarette smoking can be considered a confounder when analyzing the VOC-profile. We aimed to assess whether an e-nose can discriminate exhaled breath before and after smoking at different time periods. We enrolled 24 healthy smokers and collected their exhaled breath as follows: (a) before smoking, (b) within 5 min after smoking, (c) within 30 min after smoking, and (d) within 60 min after smoking. Exhaled breath was collected by a previously validated method and analyzed by an e-nose (Cyranose 320). By principal component analysis, significant variations in the exhaled VOC profile were shown for principal component 1 and 2 before and after smoking. Significance was higher 30 and 60 min after smoking than 5 min after (p < 0.01 and
ISSN:2079-6374
2079-6374
DOI:10.3390/bios12070520