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A Case of Hyperparathyroidism due to a Large Intrathyroid Parathyroid Adenoma with Recurrent Episodes of Acute Pancreatitis
We report a case of a 66-year-old woman who developed hyperparathyroidism due to a large intrathyroid parathyroid adenoma with episodes of acute pancreatitis. She had previously been treated for acute pancreatitis twice. Serum calcium was 12.4 mg/dL, and intact parathyroid hormone was 253 pg/dL. Ult...
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Published in: | Case reports in endocrinology 2017-01, Vol.2017 (2017), p.1-5 |
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container_issue | 2017 |
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container_title | Case reports in endocrinology |
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creator | Daimon, Makoto Morohashi, Satoko Nishi, Takashi Igawa, Akiko Sugiyama, Aya Kinoshita, Noriko Kageyama, Kazunori Kijima, Hiroshi |
description | We report a case of a 66-year-old woman who developed hyperparathyroidism due to a large intrathyroid parathyroid adenoma with episodes of acute pancreatitis. She had previously been treated for acute pancreatitis twice. Serum calcium was 12.4 mg/dL, and intact parathyroid hormone was 253 pg/dL. Ultrasonography and computed tomography of the neck with contrast enhancement revealed a soft tissue mass (28 mm transverse diameter) within the left lobe of the thyroid. 99mTc-MIBI scintigraphy demonstrated focal accumulation due to increased radiotracer uptake in the left thyroid lobe. Left hemithyroidectomy was performed. Histopathology showed no signs of invasion, and this is consistent with parathyroid adenoma. Immunostaining was positive for expression of chromogranin A and parathyroid hormone. The patient had no episode of pancreatitis after the operation. In a patient with recurrent episodes of pancreatitis, the possibility of complication with hyperparathyroidism should be considered. |
doi_str_mv | 10.1155/2017/5376741 |
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She had previously been treated for acute pancreatitis twice. Serum calcium was 12.4 mg/dL, and intact parathyroid hormone was 253 pg/dL. Ultrasonography and computed tomography of the neck with contrast enhancement revealed a soft tissue mass (28 mm transverse diameter) within the left lobe of the thyroid. 99mTc-MIBI scintigraphy demonstrated focal accumulation due to increased radiotracer uptake in the left thyroid lobe. Left hemithyroidectomy was performed. Histopathology showed no signs of invasion, and this is consistent with parathyroid adenoma. Immunostaining was positive for expression of chromogranin A and parathyroid hormone. The patient had no episode of pancreatitis after the operation. In a patient with recurrent episodes of pancreatitis, the possibility of complication with hyperparathyroidism should be considered.</description><identifier>ISSN: 2090-6501</identifier><identifier>EISSN: 2090-651X</identifier><identifier>DOI: 10.1155/2017/5376741</identifier><identifier>PMID: 28815093</identifier><language>eng</language><publisher>Cairo, Egypt: Hindawi Publishing Corporation</publisher><subject>Bone density ; Care and treatment ; Case Report ; Case reports ; Case studies ; Complications and side effects ; Cystic fibrosis ; Development and progression ; Diabetes ; Endocrine system ; Endocrinology ; Gastroenterology ; Hyperparathyroidism ; Localization ; Medicine ; Metabolism ; Mutation ; Patients ; Surgery ; Thymoma ; Thyroid gland ; Tumors ; University graduates</subject><ispartof>Case reports in endocrinology, 2017-01, Vol.2017 (2017), p.1-5</ispartof><rights>Copyright © 2017 Kazunori Kageyama et al.</rights><rights>COPYRIGHT 2017 John Wiley & Sons, Inc.</rights><rights>Copyright © 2017 Kazunori Kageyama et al.; This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.</rights><rights>Copyright © 2017 Kazunori Kageyama et al. 2017</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c611t-cf26607b09b9ee3d6d885df55e56a111105a4d551ac7bc289c0933065a87025f3</citedby><cites>FETCH-LOGICAL-c611t-cf26607b09b9ee3d6d885df55e56a111105a4d551ac7bc289c0933065a87025f3</cites><orcidid>0000-0003-0662-5231</orcidid></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.proquest.com/docview/1926424107/fulltextPDF?pq-origsite=primo$$EPDF$$P50$$Gproquest$$Hfree_for_read</linktopdf><linktohtml>$$Uhttps://www.proquest.com/docview/1926424107?pq-origsite=primo$$EHTML$$P50$$Gproquest$$Hfree_for_read</linktohtml><link.rule.ids>230,314,723,776,780,881,25731,27901,27902,36989,44566,53766,53768,74869</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/28815093$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><contributor>Capella, Carlo</contributor><creatorcontrib>Daimon, Makoto</creatorcontrib><creatorcontrib>Morohashi, Satoko</creatorcontrib><creatorcontrib>Nishi, Takashi</creatorcontrib><creatorcontrib>Igawa, Akiko</creatorcontrib><creatorcontrib>Sugiyama, Aya</creatorcontrib><creatorcontrib>Kinoshita, Noriko</creatorcontrib><creatorcontrib>Kageyama, Kazunori</creatorcontrib><creatorcontrib>Kijima, Hiroshi</creatorcontrib><title>A Case of Hyperparathyroidism due to a Large Intrathyroid Parathyroid Adenoma with Recurrent Episodes of Acute Pancreatitis</title><title>Case reports in endocrinology</title><addtitle>Case Rep Endocrinol</addtitle><description>We report a case of a 66-year-old woman who developed hyperparathyroidism due to a large intrathyroid parathyroid adenoma with episodes of acute pancreatitis. She had previously been treated for acute pancreatitis twice. Serum calcium was 12.4 mg/dL, and intact parathyroid hormone was 253 pg/dL. Ultrasonography and computed tomography of the neck with contrast enhancement revealed a soft tissue mass (28 mm transverse diameter) within the left lobe of the thyroid. 99mTc-MIBI scintigraphy demonstrated focal accumulation due to increased radiotracer uptake in the left thyroid lobe. Left hemithyroidectomy was performed. Histopathology showed no signs of invasion, and this is consistent with parathyroid adenoma. Immunostaining was positive for expression of chromogranin A and parathyroid hormone. The patient had no episode of pancreatitis after the operation. In a patient with recurrent episodes of pancreatitis, the possibility of complication with hyperparathyroidism should be considered.</description><subject>Bone density</subject><subject>Care and treatment</subject><subject>Case Report</subject><subject>Case reports</subject><subject>Case studies</subject><subject>Complications and side effects</subject><subject>Cystic fibrosis</subject><subject>Development and progression</subject><subject>Diabetes</subject><subject>Endocrine system</subject><subject>Endocrinology</subject><subject>Gastroenterology</subject><subject>Hyperparathyroidism</subject><subject>Localization</subject><subject>Medicine</subject><subject>Metabolism</subject><subject>Mutation</subject><subject>Patients</subject><subject>Surgery</subject><subject>Thymoma</subject><subject>Thyroid gland</subject><subject>Tumors</subject><subject>University graduates</subject><issn>2090-6501</issn><issn>2090-651X</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2017</creationdate><recordtype>article</recordtype><sourceid>PIMPY</sourceid><sourceid>DOA</sourceid><recordid>eNqNks-LEzEUgAdR3GXdm2cJeNTu5vdMLkIp626hoIiCt5Amb9qUzqQmGZfiP7-pra0FDyaHhPe-95EXXlW9JviGECFuKSb1rWC1rDl5Vl1SrPBICvL9-fGOyUV1ndIKlyUxZYy_rC5o0xCBFbusfo3RxCRAoUUP2w3EjYkmL7cxeOdTh9wAKAdk0MzEBaBpn49p9PmEorGDPnQGPfq8RF_ADjFCn9HdxqfgIO30YztkKEW9jWCyzz69ql60Zp3g-nBeVd8-3n2dPIxmn-6nk_FsZCUheWRbKiWu51jNFQBz0jWNcK0QIKQhZWFhuBOCGFvPLW2ULZ0xLIVpakxFy66q6d7rglnpTfSdiVsdjNe_AyEutInZ2zVoUExaTg1VSnJDsJKtYtw2gjsmCcfF9WHv2gzzDpyF3Y-sz6Tnmd4v9SL81EJwVXYRvD0IYvgxQMp6FYbYl_41UVRyygmuT9TClFf5vg1FZjufrB4LgbmihLBC3fyDKttB523oofUlflbwfl9gY0gpQnt8OMF6N1B6N1D6MFAFf_N3s0f4z_gU4N0eWPremUf_nzooDLTmRBMuCs6eACZQ2qo</recordid><startdate>20170101</startdate><enddate>20170101</enddate><creator>Daimon, Makoto</creator><creator>Morohashi, Satoko</creator><creator>Nishi, Takashi</creator><creator>Igawa, Akiko</creator><creator>Sugiyama, Aya</creator><creator>Kinoshita, Noriko</creator><creator>Kageyama, Kazunori</creator><creator>Kijima, Hiroshi</creator><general>Hindawi Publishing Corporation</general><general>Hindawi</general><general>John Wiley & Sons, Inc</general><general>Hindawi Limited</general><scope>ADJCN</scope><scope>AHFXO</scope><scope>RHU</scope><scope>RHW</scope><scope>RHX</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>3V.</scope><scope>7X7</scope><scope>7XB</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>AZQEC</scope><scope>BENPR</scope><scope>CCPQU</scope><scope>CWDGH</scope><scope>DWQXO</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>K9.</scope><scope>M0S</scope><scope>PIMPY</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>PRINS</scope><scope>5PM</scope><scope>DOA</scope><orcidid>https://orcid.org/0000-0003-0662-5231</orcidid></search><sort><creationdate>20170101</creationdate><title>A Case of Hyperparathyroidism due to a Large Intrathyroid Parathyroid Adenoma with Recurrent Episodes of Acute Pancreatitis</title><author>Daimon, Makoto ; Morohashi, Satoko ; Nishi, Takashi ; Igawa, Akiko ; Sugiyama, Aya ; Kinoshita, Noriko ; Kageyama, Kazunori ; Kijima, Hiroshi</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c611t-cf26607b09b9ee3d6d885df55e56a111105a4d551ac7bc289c0933065a87025f3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2017</creationdate><topic>Bone density</topic><topic>Care and treatment</topic><topic>Case Report</topic><topic>Case reports</topic><topic>Case studies</topic><topic>Complications and side effects</topic><topic>Cystic fibrosis</topic><topic>Development and progression</topic><topic>Diabetes</topic><topic>Endocrine system</topic><topic>Endocrinology</topic><topic>Gastroenterology</topic><topic>Hyperparathyroidism</topic><topic>Localization</topic><topic>Medicine</topic><topic>Metabolism</topic><topic>Mutation</topic><topic>Patients</topic><topic>Surgery</topic><topic>Thymoma</topic><topic>Thyroid gland</topic><topic>Tumors</topic><topic>University graduates</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Daimon, Makoto</creatorcontrib><creatorcontrib>Morohashi, Satoko</creatorcontrib><creatorcontrib>Nishi, Takashi</creatorcontrib><creatorcontrib>Igawa, Akiko</creatorcontrib><creatorcontrib>Sugiyama, Aya</creatorcontrib><creatorcontrib>Kinoshita, Noriko</creatorcontrib><creatorcontrib>Kageyama, Kazunori</creatorcontrib><creatorcontrib>Kijima, Hiroshi</creatorcontrib><collection>الدوريات العلمية والإحصائية - e-Marefa Academic and Statistical Periodicals</collection><collection>معرفة - المحتوى العربي الأكاديمي المتكامل - e-Marefa Academic Complete</collection><collection>Hindawi Publishing Complete</collection><collection>Hindawi Publishing Subscription Journals</collection><collection>Hindawi Publishing Open Access Journals</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>ProQuest Central (Corporate)</collection><collection>Health & Medical Collection</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>Hospital Premium Collection</collection><collection>Hospital Premium Collection (Alumni Edition)</collection><collection>ProQuest Central (Alumni) (purchase pre-March 2016)</collection><collection>ProQuest Central (Alumni)</collection><collection>ProQuest Central</collection><collection>ProQuest Central Essentials</collection><collection>ProQuest Central</collection><collection>ProQuest One Community College</collection><collection>Middle East & Africa Database</collection><collection>ProQuest Central</collection><collection>Health Research Premium Collection</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>Health & Medical Collection (Alumni Edition)</collection><collection>Publicly Available Content Database</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>ProQuest Central China</collection><collection>PubMed Central (Full Participant titles)</collection><collection>DOAJ Directory of Open Access Journals</collection><jtitle>Case reports in endocrinology</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Daimon, Makoto</au><au>Morohashi, Satoko</au><au>Nishi, Takashi</au><au>Igawa, Akiko</au><au>Sugiyama, Aya</au><au>Kinoshita, Noriko</au><au>Kageyama, Kazunori</au><au>Kijima, Hiroshi</au><au>Capella, Carlo</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>A Case of Hyperparathyroidism due to a Large Intrathyroid Parathyroid Adenoma with Recurrent Episodes of Acute Pancreatitis</atitle><jtitle>Case reports in endocrinology</jtitle><addtitle>Case Rep Endocrinol</addtitle><date>2017-01-01</date><risdate>2017</risdate><volume>2017</volume><issue>2017</issue><spage>1</spage><epage>5</epage><pages>1-5</pages><issn>2090-6501</issn><eissn>2090-651X</eissn><abstract>We report a case of a 66-year-old woman who developed hyperparathyroidism due to a large intrathyroid parathyroid adenoma with episodes of acute pancreatitis. She had previously been treated for acute pancreatitis twice. Serum calcium was 12.4 mg/dL, and intact parathyroid hormone was 253 pg/dL. Ultrasonography and computed tomography of the neck with contrast enhancement revealed a soft tissue mass (28 mm transverse diameter) within the left lobe of the thyroid. 99mTc-MIBI scintigraphy demonstrated focal accumulation due to increased radiotracer uptake in the left thyroid lobe. Left hemithyroidectomy was performed. Histopathology showed no signs of invasion, and this is consistent with parathyroid adenoma. Immunostaining was positive for expression of chromogranin A and parathyroid hormone. The patient had no episode of pancreatitis after the operation. In a patient with recurrent episodes of pancreatitis, the possibility of complication with hyperparathyroidism should be considered.</abstract><cop>Cairo, Egypt</cop><pub>Hindawi Publishing Corporation</pub><pmid>28815093</pmid><doi>10.1155/2017/5376741</doi><tpages>5</tpages><orcidid>https://orcid.org/0000-0003-0662-5231</orcidid><oa>free_for_read</oa></addata></record> |
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subjects | Bone density Care and treatment Case Report Case reports Case studies Complications and side effects Cystic fibrosis Development and progression Diabetes Endocrine system Endocrinology Gastroenterology Hyperparathyroidism Localization Medicine Metabolism Mutation Patients Surgery Thymoma Thyroid gland Tumors University graduates |
title | A Case of Hyperparathyroidism due to a Large Intrathyroid Parathyroid Adenoma with Recurrent Episodes of Acute Pancreatitis |
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