Initial-Stage Primary Intraosseous Squamous Cell Carcinoma Derived from Odontogenic Keratocyst with Unusual Keratoameloblastomatous Change of the Maxilla: A Case Report and Literature Discussion

Primary intraosseous squamous cell carcinoma (PIOSCC) is a rare malignant neoplasm derived from odontogenic epithelial remnants in the central jaw bone. Most PIOSCCs originate from odontogenic cysts with a nonkeratinized epithelial lining, especially from radicular/residual and dentigerous cysts. Th...

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Bibliographic Details
Published in:Case reports in otolaryngology 2018-01, Vol.2018 (2018), p.1-6
Main Authors: Kusama, Kaoru, Sakashita, Hideaki, Suzuki, Seiji, Takizawa, Shota, Ide, Fumio, Kikuchi, Kentaro, Li, Tie-Jun
Format: Article
Language:English
Subjects:
Bone marrow
Case Report
Case reports
Cysts
Diagnosis
Maxillofacial surgery
Medicine
Metastasis
Neck
Pathology
Squamous cell carcinoma
Surgery
Tumors
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Summary:Primary intraosseous squamous cell carcinoma (PIOSCC) is a rare malignant neoplasm derived from odontogenic epithelial remnants in the central jaw bone. Most PIOSCCs originate from odontogenic cysts with a nonkeratinized epithelial lining, especially from radicular/residual and dentigerous cysts. There have been few reports of PIOSCCs derived from the odontogenic keratocyst (OKC), particularly those describing pathological features at the initial stage. The diagnosis of PIOSCC is difficult and based on exclusion of other carcinomas, including metastatic tumors from other primary sites. Here, we report an extremely rare case of initial-stage PIOSCC derived from the OKC with unusual keratoameloblastomatous change of the maxilla.
ISSN:2090-6765
2090-6773
DOI:10.1155/2018/7959230