Chemical Composition and Biological Activities of Prangos ferulacea Essential Oils

Prangos ferulacea (L.) Lindl, which belongs to the Apiaceae family, is a species that mainly grows in the eastern Mediterranean region and in western Asia. It has been largely used in traditional medicine in several countries and it has been shown to possess several interesting biological properties...

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Bibliographic Details
Published in:Molecules (Basel, Switzerland) Switzerland), 2022-11, Vol.27 (21), p.7430
Main Authors: Badalamenti, Natale, Maresca, Viviana, Di Napoli, Michela, Bruno, Maurizio, Basile, Adriana, Zanfardino, Anna
Format: Article
Language:English
Subjects:
(Z)-β-ocimene
Antiinfectives and antibacterials
Antimicrobial activity
Antimicrobial agents
antioxidant activity
Antioxidants
Apiaceae
Bacteria
Biological properties
Catalase
Chemical composition
Essential oils
Flavonoids
Flowers
Flowers & plants
Functional foods & nutraceuticals
GC-MS
Glutathione transferase
Gram-negative bacteria
Gram-positive bacteria
Hydrocarbons
Metabolites
Ocimene
Oils & fats
Pharmacology
Polysiphonia ferulacea
Prangos ferulacea
Superoxide dismutase
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Summary:Prangos ferulacea (L.) Lindl, which belongs to the Apiaceae family, is a species that mainly grows in the eastern Mediterranean region and in western Asia. It has been largely used in traditional medicine in several countries and it has been shown to possess several interesting biological properties. With the aim to provide new insights into the phytochemistry and pharmacology of this species, the essential oils of flowers and leaves from a local accession that grows in Sicily (Italy) and has not yet been previously studied were investigated. The chemical composition of both oils, obtained by hydrodistillation from the leaves and flowers, was evaluated by GC-MS. This analysis allowed us to identify a new chemotype, characterized by a large amount of (Z)-β-ocimene. Furthermore, these essential oils have been tested for their possible antimicrobial and antioxidant activity. P. ferulacea essential oils exhibit moderate antimicrobial activity; in particular, the flower essential oil is harmful at low and wide spectrum concentrations. They also exhibit good antioxidant activity in vitro and in particular, it has been shown that the essential oils of the flowers and leaves of P. ferulacea caused a decrease in ROS and an increase in the activity of superoxide dismutase (SOD), catalase (CAT) and glutathione S-transferase (GST) in OZ-stimulated PMNs. Therefore, these essential oils could be considered as promising candidates for pharmaceutical and nutraceutical preparations.
ISSN:1420-3049
1420-3049
DOI:10.3390/molecules27217430