Expression of Serum sLOX-1 in Patients with Non-Small-Cell Lung Cancer and Its Correlation with Lipid Metabolism

Objective. The aim of this study was to investigate the expression level of soluble LOX-1 (sLOX-1) in the serum of non-small-cell lung cancer (NSCLC) patients and its correlation with lipid metabolism. Methods. 99 inpatients with NSCLC and 81 healthy controls were enrolled in this study. The levels...

Full description

Saved in:
Bibliographic Details
Published in:Canadian respiratory journal 2022-04, Vol.2022, p.6619331-9
Main Authors: Hao, Fangfang, Chen, Jinliang, Wu, Jinnan, Ge, Xin, Lv, Xuedong, Zhang, Dongmei, Chen, Jianrong
Format: Article
Language:English
Subjects:
Cancer therapies
Carcinoembryonic Antigen - metabolism
Carcinoma, Non-Small-Cell Lung
Cardiovascular disease
Care and treatment
CEA (Oncology)
Cell receptors
Cholesterol
Comparative analysis
Development and progression
Diagnosis
Drug dosages
Health aspects
Health care
Heart
High density lipoprotein
Hormone replacement therapy
Hospital patients
Hospitals
Humans
Lectins
Lipid Metabolism
Lipids
Lipoproteins
Lipoproteins, LDL - metabolism
Low density lipoproteins
Lung cancer
Lung cancer, Non-small cell
Lung Neoplasms
Measurement
Medical prognosis
Metabolism
Metastasis
Normal distribution
Physiological aspects
Scavenger Receptors, Class E - metabolism
Serodiagnosis
Signal transduction
Triglycerides
Tumors
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Objective. The aim of this study was to investigate the expression level of soluble LOX-1 (sLOX-1) in the serum of non-small-cell lung cancer (NSCLC) patients and its correlation with lipid metabolism. Methods. 99 inpatients with NSCLC and 81 healthy controls were enrolled in this study. The levels of serum sLOX-1 were compared between the two groups, and the correlation of sLOX-1 with clinicopathological characteristics, blood lipid indices, and carcinoembryonic antigen was analyzed. Results. Compared with the healthy controls, sLOX-1, low-density lipoprotein, triglyceride, and carcinoembryonic antigen in the patients with NSCLC were significantly higher (p 
ISSN:1198-2241
1916-7245
DOI:10.1155/2022/6619331