Generation of Nanoliter Droplets on Demand at Hundred-Hz Frequencies

We describe a precision micropump for generation of precisely metered micro-aliquots of liquid at high rates. The use of custom designed piezoelectric valves positioned externally to the microfluidic chip allows for on-demand formation of micro-droplets with online control of their individual volume...

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Bibliographic Details
Published in:Micromachines (Basel) 2014-12, Vol.5 (4), p.1002-1011
Main Authors: Jakiela, Slawomir, Debski, Pawel R, Dabrowski, Bogdan, Garstecki, Piotr
Format: Article
Language:English
Subjects:
Combinatorial analysis
Control valves
Demand
Droplets
droplets on demand
Microfluidics
Micropumps
nanoliter droplets
Nanostructure
piezoelectric valve
Tuning
Valves
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Summary:We describe a precision micropump for generation of precisely metered micro-aliquots of liquid at high rates. The use of custom designed piezoelectric valves positioned externally to the microfluidic chip allows for on-demand formation of micro-droplets with online control of their individual volumes from nLs to μLs at frequencies up to 400 Hz. The system offers precision of administering volumes of 1% and of time of emission of
ISSN:2072-666X
2072-666X
DOI:10.3390/mi5041002