Hypertensive retinopathy as the initial presentation of neuroblastoma

To describe a case of a patient who presented with hypertensive retinopathy and was found to have neuroblastoma. Neuroblastoma has three main ocular presentations. As a primary disease, it can present with a paraneoplastic syndrome in the form of opsoclonus, or it can present as a Horner's synd...

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Bibliographic Details
Published in:American journal of ophthalmology case reports 2017-09, Vol.7 (C), p.123-125
Main Authors: Djougarian, Anna, Kodsi, Sylvia
Format: Article
Language:English
Subjects:
Case report
Hypertensive retinopathy
Neuroblastoma
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Summary:To describe a case of a patient who presented with hypertensive retinopathy and was found to have neuroblastoma. Neuroblastoma has three main ocular presentations. As a primary disease, it can present with a paraneoplastic syndrome in the form of opsoclonus, or it can present as a Horner's syndrome from its effect on the cervical sympathetic ganglia. Metastatic disease can present as a triad of periorbital edema, ecchymosis and proptosis from orbital bone involvement. Hypertension is a rare systemic presentation of neuroblastoma. We report the case of a two-year-old girl whose initial presentation of neuroblastoma was hypertensive retinopathy. To our knowledge, this is the first reported case of neuroblastoma presenting as hypertensive retinopathy. Our case highlights the importance of a multidisciplinary approach and thorough systemic work up of ocular findings in order to arrive at an appropriate diagnosis.
ISSN:2451-9936
2451-9936
DOI:10.1016/j.ajoc.2017.06.008