Association between lifestyle and thyroid dysfunction: a cross-sectional epidemiologic study in the She ethnic minority group of Fujian Province in China

• Published in: BMC endocrine disorders 2019-07, Vol.19 (1), p.83-83, Article 83
• Main Authors: Huang, Yanling, Cai, Liangchun, Zheng, Yuanyuan, Pan, Jinxing, Li, Liantao, Zong, Liyao, Lin, Wei, Liang, Jixing, Huang, Huibin, Wen, Junping, Chen, Gang
• Format: Article
• Language: English
• Subjects: Adult; Aged; Aged, 80 and over; Antibodies; Autoantibodies - blood; Body mass index; Body weight; Care and treatment; China - epidemiology; Cholesterol; Complications and side effects; Cross-Sectional Studies; Drinking (Alcoholic beverages); Education; Epidemiologic study; Ethnic Groups - statistics & numerical data; Female; Follow-Up Studies; Headache; Health surveys; Humans; Hyperthyroidism; Hypothyroidism; Insomnia; Life Style; Lifestyles; Male; Middle Aged; Minorities; Minority Groups - statistics & numerical data; Patient outcomes; Peroxidase; Physiological aspects; Prevalence; Prognosis; Regression analysis; Smoking; Thyroid diseases; Thyroid Diseases - blood; Thyroid Diseases - epidemiology; Thyroid hormones; Thyroid peroxidase antibody (TPOAb); Triglycerides; Weight loss maintenance; Young Adult
• ISSN: 1472-6823; 1472-6823
• DOI: 10.1186/s12902-019-0414-z

Thyroid dysfunction is one of the prevalent endocrine disorders. The relationship between lifestyle factors and thyroid dysfunction was not clear and some of the factors seemed paradoxical. We conducted this population-based study using data from 5154 She ethnic minority people who had entered into the epidemic survey of diabetes between July 2007 to September 2009. Life style information was collected using a standard questionnaire. Body mass index (BMI), Blood pressure and serum TSH, TPOAb, triglycerides (TG), total cholesterol (TC) and high-density lipoprotein cholesterol (HDL) were collected. The study showed that people who drank, had higher education or suffered from insomnia have lower incidence of hyperthyroidism. On the other hand, smoking, alcohol consumption, exercise, undergoing weight watch and chronic headache were associated with decreased incidence of hypothyroidism. Using multivariable logistic regression analysis, we found that alcohol consumption was associated with decreased probability of hyperthyroidism, hypothyroidism, as well as positive TPOAb. The amounts of cigarettes smoked daily displayed a positive correlation with hyperthyroidism among smokers. Accordingly, smoking seemed to be associated with decreased risk for hypothyroidism and positive TPOAb. Exercise and maintaining a healthy weight might have a beneficial effect on thyroid health. Interestingly, daily staple amount showed an inverse correlation with incidence of positive TPOAb. Within the Chinese She ethnic minority, we found associations between different lifestyle factors and the incidence of different thyroid diseases. Understanding the nature of these associations requires further investigations.