Solitary sclerosis presenting as isolated spontaneous paroxysmal dysarthria

Paroxysmal dysarthria and ataxia (PDA) is a rare syndrome characterized by brief, stereotyped episodes of slurred speech, clumsiness with extremities, or vertigo. It is usually observed in young patients suffering from multiple sclerosis with numerous lesions. PDA is challenging to identify in those...

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Bibliographic Details
Published in:eNeurologicalSci 2019-03, Vol.14, p.98-100
Main Authors: Xia, Yuanxuan, Shoemaker, Thomas, Gorelick, Noah, McArthur, Justin C.
Format: Article
Language:English
Subjects:
Case Report
Multiple sclerosis
Paroxysmal dysarthria and ataxia
Solitary sclerosis
Spontaneous paroxysmal dysarthria
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Summary:Paroxysmal dysarthria and ataxia (PDA) is a rare syndrome characterized by brief, stereotyped episodes of slurred speech, clumsiness with extremities, or vertigo. It is usually observed in young patients suffering from multiple sclerosis with numerous lesions. PDA is challenging to identify in those presenting with atypical patterns. Here, a non-ataxic variant of PDA in an otherwise neurologically healthy elderly man is presented who had a single midbrain lesion. A broad diagnostic workup illustrates the challenges of identifying PDA. Teaching points emphasize the significance of the midbrain lesion and response to anti-epileptic medication. •Paroxysmal Dysarthria and Ataxia (PDA) is a very rare MS-related paroxysm•Case of a non-ataxic PDA variant in an otherwise neurologically healthy elderly man•Video clearly shows the symptoms of this Spontaneous Paroxysmal Dysarthria•Solitary midbrain lesions and responsiveness to anti-epileptics are key features
ISSN:2405-6502
2405-6502
DOI:10.1016/j.ensci.2019.01.001