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Transcription and Post-translational Regulation of Autophagy in Insects

Autophagy attracts great attention, and numerous progresses have been obtained in the last two decades. Autophagy is implicated in mammalian neurodegenerative diseases, tumorigenesis, as well as development in insects. The regulatory mechanism of autophagy is well documented in yeast and mammals, wh...

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Published in:Frontiers in physiology 2022-02, Vol.13, p.825202-825202
Main Authors: Li, Rongsong, Xiao, Yang, Li, Kang, Tian, Ling
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description Autophagy attracts great attention, and numerous progresses have been obtained in the last two decades. Autophagy is implicated in mammalian neurodegenerative diseases, tumorigenesis, as well as development in insects. The regulatory mechanism of autophagy is well documented in yeast and mammals, whereas it is not fully illustrated in insects. and are the two well-studied insects for autophagy, and several insect-mammalian evolutionarily conserved or insect-specific mechanisms in regulating autophagy are reported. In this review, we summarize the most recent studies of autophagy regulated at both transcriptional and post-translational levels by insect hormone in cooperation with other signals, such as nutrient, which will provide a reference and deep thinking for studies on autophagy in insects.
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subjects autophagy
insect hormone
nutrient signal
Physiology
post-translational modification
transcription
title Transcription and Post-translational Regulation of Autophagy in Insects
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