Evaluation of flavonoids and diverse antioxidant activities of Sonchus arvensis

• Published in: BMC chemistry 2012-10, Vol.6 (1), p.126-126, Article 126
• Main Author: Khan, Rahmat Ali
• Format: Article
• Language: English
• Subjects: Antioxidants; Catechins; Chemistry; Chemistry and Materials Science; Chemistry/Food Science; Correlation; DPPH; Flavonoids; Free radicals; HPLC; Human; LSD; Lysergic acid diethylamide; Mortality; Organic and Medicinal Chemistry; Oxidative stress; Polyphenols; Radicals; Research Article; Scavenging; Sonchus; Sonchus arvensis; Studies; Total antioxidant activity
• ISSN: 1752-153X; 1752-153X; 2661-801X
• DOI: 10.1186/1752-153X-6-126

Background Sonchus arvensis is used in the treatment of various human aliments as a traditional medicine in Pakistan. In the study its various fractions are characterized for scavenging of diverse free radicals. Results Results of the present study revealed that various fractions of Sonchus arvensis significantly scavenged the free radicals (DPPH·, ABTS·+, ·OH, superoxide), however its methanolic fraction is more potent than other fractions. Significant correlation was found between DPPH·, ABTS·+, superoxide radical and total antioxidant activity with total flavonoids and phenolics contents. Phytochmical analysis revealed the presence kaempferol, quercetin, orientin, rutin, hyperoside, catechin and myricetin. Conclusion From the present data it is concluded that various fractions of Sonchus arvensis significantly scavenged the free radical, which might be due the presence of polyphenolic constituent.