Development and evaluation of an online questionnaire to identify women at high and low risk of developing gestational diabetes mellitus

Established risk factors for Gestational Diabetes Mellitus (GDM) include age, ethnicity, family history of diabetes and previous GDM. Additional significant influences have recently been demonstrated in the literature. The oral glucose tolerance test (OGTT) used for GDM diagnosis has sub-optimal sen...

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Bibliographic Details
Published in:BMC pregnancy and childbirth 2022-04, Vol.22 (1), p.321-321, Article 321
Main Authors: Di Filippo, Daria, Bell, Chloe, Chang, Melissa Han Yiin, Darling, Justine, Henry, Amanda, Welsh, Alec
Format: Article
Language:English
Subjects:
Blood Glucose
Blood Glucose Self-Monitoring
Body mass index
Consent
Diabetes, Gestational - diagnosis
Ethnicity
Exercise
Female
Food
Gestational diabetes
Gestational diabetes mellitus
Glucose
Glucose monitoring
Humans
Hyperglycemia
Insulin
Mass Screening
Obesity
Obstetrics
Oral glucose tolerance test
Physical fitness
Polycystic ovary syndrome
Pregnancy
Questionnaire
Questionnaires
Risk Factors
Screening, continuous glucose monitoring
Software
Statistical analysis
Womens health
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Summary:Established risk factors for Gestational Diabetes Mellitus (GDM) include age, ethnicity, family history of diabetes and previous GDM. Additional significant influences have recently been demonstrated in the literature. The oral glucose tolerance test (OGTT) used for GDM diagnosis has sub-optimal sensitivity and specificity, thus often results in GDM misdiagnoses. Comprehensive screening of risk factors may allow more targeted monitoring and more accurate diagnoses, preventing the devastating consequences of untreated or misdiagnosed GDM. We aimed to develop a comprehensive online questionnaire of GDM risk factors and triangulate it with the OGTT and continuous glucose monitoring (CGM) parameters to better evaluate GDM risk and diagnosis. Pregnant women participating in two studies on the use of CGM for GDM were invited to complete the online questionnaire. A risk score, based on published literature, was calculated for each participant response and compared with the OGTT result. A total risk score (TRS) was then calculated as a normalised sum of all risk factors. Triangulation of OGTT, TRS and CGM score of variability (CGMSV) was analysed to expand evaluation of OGTT results. Fifty one women completed the questionnaire; 29 were identified as 'high-risk' for GDM. High-risk ethnic background (p 
ISSN:1471-2393
1471-2393
DOI:10.1186/s12884-022-04629-8