Non-Invasive Nanoparticle Imaging Technologies for Cosmetic and Skin Care Products

The nanotechnology field is growing at an unprecedented rate. This is resulting in significant benefits in skin care products and formulations. Likewise, imaging technology is also advancing. The convergence of these fields offers a unique opportunity to observe and quantify the interactions of nano...

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Bibliographic Details
Published in:Cosmetics (Basel) 2015-09, Vol.2 (3), p.196-210
Main Authors: Lin, Lynlee, Nufer, Kaitlin, Tomihara, Shoko, Prow, Tarl
Format: Article
Language:English
Subjects:
Confocal microscopy
cosmetic testing
Cosmetics
Cosmetics industry
Electron microscopy
Gold
Hair
human volunteers
imaging
in vivo
Investigations
Lasers
Mass spectroscopy
Medical imaging
Melanoma
Morphology
Nanoparticles
non-invasive
Scanning electron microscopy
Skin
Skin care products
Skin tests
Spectrum analysis
Zinc oxides
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Summary:The nanotechnology field is growing at an unprecedented rate. This is resulting in significant benefits in skin care products and formulations. Likewise, imaging technology is also advancing. The convergence of these fields offers a unique opportunity to observe and quantify the interactions of nanoparticles within cosmetic and skin care formulations. More importantly, imaging technology holds tremendous promise for understanding how formulated nanoparticles interact with our skin. Imaging technologies can be broken into two major groups that include those that require invasive sample collection and processing (e.g., electron microscopy, mass spectrometry, and super-resolution structured illumination microscopy) and those that can be used in non-invasive data collection settings. Fluorescence microscopy, confocal microscopy, coherent anti-Stokes Raman scattering spectroscopy and optical coherence tomography fall into the latter category and are the focus of this review in the context of skin care product and cosmetics testing. Cosmetic and skin care product testing is most informative when carried out in volunteers. This makes invasive or disruptive analysis techniques unfeasible and supports the use of non-invasive imaging technologies. The combination of non-invasive imaging and minimally invasive microbiopsy sampling for combined imaging and molecular data is the future of skin care product testing.
ISSN:2079-9284
2079-9284
DOI:10.3390/cosmetics2030196