Surgical management and clinical outcome of cervical, thoracic and thoracolumbar spinal tuberculosis in a middle-European adult population

Spinal tuberculosis is due to globalization no longer a disease limited to developing nations. It remains in Germany a rarity and still a difficult diagnosis. Here we analyzed patients with spinal tuberculosis treated at our neurosurgical department. According to the infected anatomic segment, patie...

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Bibliographic Details
Published in:Scientific reports 2023-04, Vol.13 (1), p.7000-7000, Article 7000
Main Authors: Kilinc, Fatma, Setzer, Matthias, Behmanesh, Bedjan, Jussen, Daniel, Geßler, Florian, Prinz, Vincent, Czabanka, Marcus
Format: Article
Language:English
Subjects:
692/700/139
692/700/459
692/700/784
Adult
Back pain
Chronic pain
Clinical outcomes
Compression
Developing countries
Differential diagnosis
Globalization
Humanities and Social Sciences
Humans
Instrumentation
LDCs
Lumbar Vertebrae - surgery
Medical treatment
multidisciplinary
Neurosurgery
Patients
Retrospective Studies
Science
Science (multidisciplinary)
Spinal Fusion
Surgery
Thoracic Vertebrae - surgery
Thorax
Treatment Outcome
Tuberculosis
Tuberculosis, Spinal - surgery
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Summary:Spinal tuberculosis is due to globalization no longer a disease limited to developing nations. It remains in Germany a rarity and still a difficult diagnosis. Here we analyzed patients with spinal tuberculosis treated at our neurosurgical department. According to the infected anatomic segment, patients were assigned in one of three groups. Surgery was performed when neurological deficit due to mechanical compression, deformity, instability, severe pain, necrotic bone or failure to respond to anti-tuberculous treatment were observed. We identified 34 patients with spinal tuberculosis who underwent surgical treatment. In the cervical spinal tuberculosis group, there were 15 cases (46.9%) In most cases treatment consisted of spinal instrumentation. In the thoracic group, 10 cases (29.4%) were observed. The treatment was performed by dorsolateral spinal instrumentation. For the thoracolumbar group, 9 cases (26.4%) were observed. In most cases dorsolateral spinal instrumentation was performed. One patient in the first group and one patient in the third group relapsed after operation. A second surgery was necessary. Patients with chronic back pain, immigration background and/or neurological deficit spinal TB should be considered as a differential diagnosis. Combined surgical intervention and medical treatment is associated with a favorable outcome.
ISSN:2045-2322
2045-2322
DOI:10.1038/s41598-023-34178-9