Loading…

Diagnostic accuracy of palpation versus ultrasound-guided fine needle aspiration biopsy for diagnosis of malignancy in thyroid nodules: a systematic review and meta-analysis

Thyroid nodule is a common health problem in endocrinology. Thyroid fine-needle aspiration biopsy (FNAB) cytology performed by palpation guided FNAB (PGFNAB) and ultrasound-guided FNAB (USGFNAB) are the preferred examinations for the diagnosis of thyroid cancer and part of the integration of the cur...

Full description

Saved in:
Bibliographic Details
Published in:BMC endocrine disorders 2022-07, Vol.22 (1), p.1-181, Article 181
Main Authors: Tarigan, Tri Juli Edi, Anwar, Budiman Syaeful, Sinto, Robert, Wisnu, Wismandari
Format: Article
Language:English
Subjects:
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
cited_by cdi_FETCH-LOGICAL-c540t-41687a5df149c72384183c02116271346f5b08daf5c8b75d67a1aa931f5ebc743
cites cdi_FETCH-LOGICAL-c540t-41687a5df149c72384183c02116271346f5b08daf5c8b75d67a1aa931f5ebc743
container_end_page 181
container_issue 1
container_start_page 1
container_title BMC endocrine disorders
container_volume 22
creator Tarigan, Tri Juli Edi
Anwar, Budiman Syaeful
Sinto, Robert
Wisnu, Wismandari
description Thyroid nodule is a common health problem in endocrinology. Thyroid fine-needle aspiration biopsy (FNAB) cytology performed by palpation guided FNAB (PGFNAB) and ultrasound-guided FNAB (USGFNAB) are the preferred examinations for the diagnosis of thyroid cancer and part of the integration of the current thyroid nodule assessment. Although studies have shown USGFNAB to be more accurate than PGFNAB, inconsistencies from several studies and clinical guidelines still exist. The purpose of this study is to compare the diagnostic accuracy of Palpation versus Ultrasound-Guided Fine Needle Aspiration Biopsy in diagnosing malignancy of thyroid nodules. The systematic review and meta-analysis were prepared based on the PRISMA standards. Literature searches were carried out on three online databases (Pubmed/MEDLINE, Embase, and Proquest) and grey literatures. Data extraction was carried out manually from various studies that met the eligibility, followed by analysis to obtain pooled data on sensitivity, specificity, Diagnostic Odds Ratio (DOR) and Area Under Curve (AUC), and the comparison of the two methods. Total of 2517 articles were obtained, with 11 studies were included in this systematic review. The total sample was 2382, including 1128 subjects using PGFNAB and 1254 subjects using USGFNAB. The risk of bias was assessed using QUADAS-2 with mild-moderate results. The results of sensitivity, specificity, AUC and DOR in diagnosing thyroid nodules using PGFNAB were 76% (95% CI, 49–89%), 77% (95% CI, 56–95%), 0.827 and 11.6 (95% CI, 6–21) respectively. The results of sensitivity, specificity, AUC and DOR in diagnosing thyroid nodules using USGFNAB were 90% (95% CI, 81–95%), 80% (95% CI, 66–89%), 0.92 and 40 (95% CI, 23–69), respectively the results of the comparison test between PGFNAB and USGFNAB; Tsens USGFNAB of 0.99 ( p  = 0.023), AUC difference test of 0.093 ( p  = 0.000023). The diagnostic accuracy of USGFNAB is higher than PGFNAB in diagnosing malignancy of thyroid nodules. If it is accessible, the author recommends using USGFNAB as a diagnostic tool for thyroid nodules.
doi_str_mv 10.1186/s12902-022-01085-5
format article
fullrecord <record><control><sourceid>gale_doaj_</sourceid><recordid>TN_cdi_doaj_primary_oai_doaj_org_article_eb3c4dac99d9407dab42f8c4d67edf85</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><galeid>A710620318</galeid><doaj_id>oai_doaj_org_article_eb3c4dac99d9407dab42f8c4d67edf85</doaj_id><sourcerecordid>A710620318</sourcerecordid><originalsourceid>FETCH-LOGICAL-c540t-41687a5df149c72384183c02116271346f5b08daf5c8b75d67a1aa931f5ebc743</originalsourceid><addsrcrecordid>eNptkk2P1SAUhhujccarf8AViRs3HYGWFlyYTMavSSZxo2tyykeHmxYqtNf0R_kf5d5O1GsMIZDDex4Oh7coXhJ8RQhv3iRCBaYlpnkSzFnJHhWXpG5p2XBaPf5rf1E8S2mPMWk5xU-Li4rxuhKMXRY_3zvofUizUwiUWiKoFQWLJhgmmF3w6GBiWhJahjlCCovXZb84bTSyzhvkjdGDQZAmFzd958KUVmRDRHpju3QkjjC43oPPfOfRfL_G4DTyQS-DSW8RoLSm2YxwrCSagzM_EHiNRjNDCR6GNXOeF08sDMm8eFh3xbePH77efC7vvny6vbm-KxWr8VzWpOEtMG1JLVRLK14TXilMCWloS6q6sazDXINlinct000LBEBUxDLTqbaudsXtxtUB9nKKboS4ygBOngIh9hJiLnQw0nSVqjUoIbSocauhq6nlOdS0RlvOMuvdxpqWbjRaGZ8bOZxBz0-8u5d9OEhx_N0T4PUDIIbvi0mzHF1SZhjAm7AkSRtB6oY2VGTpq3-k-7DE3LxNxagQgv5R9ZAf4LwN-V51hMrrluCG4ir3a1dc_UeVhzajU8Eb63L8LIFuCSqGlKKxv99IsDwaVm6Gldmw8mRYyapfE7_f6Q</addsrcrecordid><sourcetype>Open Website</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>2691529992</pqid></control><display><type>article</type><title>Diagnostic accuracy of palpation versus ultrasound-guided fine needle aspiration biopsy for diagnosis of malignancy in thyroid nodules: a systematic review and meta-analysis</title><source>Publicly Available Content Database</source><source>PubMed Central</source><creator>Tarigan, Tri Juli Edi ; Anwar, Budiman Syaeful ; Sinto, Robert ; Wisnu, Wismandari</creator><creatorcontrib>Tarigan, Tri Juli Edi ; Anwar, Budiman Syaeful ; Sinto, Robert ; Wisnu, Wismandari</creatorcontrib><description>Thyroid nodule is a common health problem in endocrinology. Thyroid fine-needle aspiration biopsy (FNAB) cytology performed by palpation guided FNAB (PGFNAB) and ultrasound-guided FNAB (USGFNAB) are the preferred examinations for the diagnosis of thyroid cancer and part of the integration of the current thyroid nodule assessment. Although studies have shown USGFNAB to be more accurate than PGFNAB, inconsistencies from several studies and clinical guidelines still exist. The purpose of this study is to compare the diagnostic accuracy of Palpation versus Ultrasound-Guided Fine Needle Aspiration Biopsy in diagnosing malignancy of thyroid nodules. The systematic review and meta-analysis were prepared based on the PRISMA standards. Literature searches were carried out on three online databases (Pubmed/MEDLINE, Embase, and Proquest) and grey literatures. Data extraction was carried out manually from various studies that met the eligibility, followed by analysis to obtain pooled data on sensitivity, specificity, Diagnostic Odds Ratio (DOR) and Area Under Curve (AUC), and the comparison of the two methods. Total of 2517 articles were obtained, with 11 studies were included in this systematic review. The total sample was 2382, including 1128 subjects using PGFNAB and 1254 subjects using USGFNAB. The risk of bias was assessed using QUADAS-2 with mild-moderate results. The results of sensitivity, specificity, AUC and DOR in diagnosing thyroid nodules using PGFNAB were 76% (95% CI, 49–89%), 77% (95% CI, 56–95%), 0.827 and 11.6 (95% CI, 6–21) respectively. The results of sensitivity, specificity, AUC and DOR in diagnosing thyroid nodules using USGFNAB were 90% (95% CI, 81–95%), 80% (95% CI, 66–89%), 0.92 and 40 (95% CI, 23–69), respectively the results of the comparison test between PGFNAB and USGFNAB; Tsens USGFNAB of 0.99 ( p  = 0.023), AUC difference test of 0.093 ( p  = 0.000023). The diagnostic accuracy of USGFNAB is higher than PGFNAB in diagnosing malignancy of thyroid nodules. If it is accessible, the author recommends using USGFNAB as a diagnostic tool for thyroid nodules.</description><identifier>ISSN: 1472-6823</identifier><identifier>EISSN: 1472-6823</identifier><identifier>DOI: 10.1186/s12902-022-01085-5</identifier><identifier>PMID: 35843955</identifier><language>eng</language><publisher>London: BioMed Central Ltd</publisher><subject>Accuracy ; Analysis ; Bias ; Biopsy ; Cancer ; Cytology ; Diagnosis ; Endocrinology ; Fine-needle aspiration biopsy ; Grey literature ; Histopathology ; Malignancy ; Meta-analysis ; Nodules ; Oncology, Experimental ; Palpable versus USG guided ; Patients ; Practice guidelines (Medicine) ; Researchers ; Reviews ; Software ; Statistical analysis ; Surgery ; Systematic review ; Thyroid cancer ; Thyroid gland ; Thyroid nodules ; Ultrasonic imaging ; Ultrasound</subject><ispartof>BMC endocrine disorders, 2022-07, Vol.22 (1), p.1-181, Article 181</ispartof><rights>COPYRIGHT 2022 BioMed Central Ltd.</rights><rights>2022. This work is licensed under http://creativecommons.org/licenses/by/4.0/ (the “License”). Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License.</rights><rights>The Author(s) 2022</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c540t-41687a5df149c72384183c02116271346f5b08daf5c8b75d67a1aa931f5ebc743</citedby><cites>FETCH-LOGICAL-c540t-41687a5df149c72384183c02116271346f5b08daf5c8b75d67a1aa931f5ebc743</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC9290285/pdf/$$EPDF$$P50$$Gpubmedcentral$$Hfree_for_read</linktopdf><linktohtml>$$Uhttps://www.proquest.com/docview/2691529992?pq-origsite=primo$$EHTML$$P50$$Gproquest$$Hfree_for_read</linktohtml><link.rule.ids>230,314,727,780,784,885,25753,27924,27925,37012,37013,44590,53791,53793</link.rule.ids></links><search><creatorcontrib>Tarigan, Tri Juli Edi</creatorcontrib><creatorcontrib>Anwar, Budiman Syaeful</creatorcontrib><creatorcontrib>Sinto, Robert</creatorcontrib><creatorcontrib>Wisnu, Wismandari</creatorcontrib><title>Diagnostic accuracy of palpation versus ultrasound-guided fine needle aspiration biopsy for diagnosis of malignancy in thyroid nodules: a systematic review and meta-analysis</title><title>BMC endocrine disorders</title><description>Thyroid nodule is a common health problem in endocrinology. Thyroid fine-needle aspiration biopsy (FNAB) cytology performed by palpation guided FNAB (PGFNAB) and ultrasound-guided FNAB (USGFNAB) are the preferred examinations for the diagnosis of thyroid cancer and part of the integration of the current thyroid nodule assessment. Although studies have shown USGFNAB to be more accurate than PGFNAB, inconsistencies from several studies and clinical guidelines still exist. The purpose of this study is to compare the diagnostic accuracy of Palpation versus Ultrasound-Guided Fine Needle Aspiration Biopsy in diagnosing malignancy of thyroid nodules. The systematic review and meta-analysis were prepared based on the PRISMA standards. Literature searches were carried out on three online databases (Pubmed/MEDLINE, Embase, and Proquest) and grey literatures. Data extraction was carried out manually from various studies that met the eligibility, followed by analysis to obtain pooled data on sensitivity, specificity, Diagnostic Odds Ratio (DOR) and Area Under Curve (AUC), and the comparison of the two methods. Total of 2517 articles were obtained, with 11 studies were included in this systematic review. The total sample was 2382, including 1128 subjects using PGFNAB and 1254 subjects using USGFNAB. The risk of bias was assessed using QUADAS-2 with mild-moderate results. The results of sensitivity, specificity, AUC and DOR in diagnosing thyroid nodules using PGFNAB were 76% (95% CI, 49–89%), 77% (95% CI, 56–95%), 0.827 and 11.6 (95% CI, 6–21) respectively. The results of sensitivity, specificity, AUC and DOR in diagnosing thyroid nodules using USGFNAB were 90% (95% CI, 81–95%), 80% (95% CI, 66–89%), 0.92 and 40 (95% CI, 23–69), respectively the results of the comparison test between PGFNAB and USGFNAB; Tsens USGFNAB of 0.99 ( p  = 0.023), AUC difference test of 0.093 ( p  = 0.000023). The diagnostic accuracy of USGFNAB is higher than PGFNAB in diagnosing malignancy of thyroid nodules. If it is accessible, the author recommends using USGFNAB as a diagnostic tool for thyroid nodules.</description><subject>Accuracy</subject><subject>Analysis</subject><subject>Bias</subject><subject>Biopsy</subject><subject>Cancer</subject><subject>Cytology</subject><subject>Diagnosis</subject><subject>Endocrinology</subject><subject>Fine-needle aspiration biopsy</subject><subject>Grey literature</subject><subject>Histopathology</subject><subject>Malignancy</subject><subject>Meta-analysis</subject><subject>Nodules</subject><subject>Oncology, Experimental</subject><subject>Palpable versus USG guided</subject><subject>Patients</subject><subject>Practice guidelines (Medicine)</subject><subject>Researchers</subject><subject>Reviews</subject><subject>Software</subject><subject>Statistical analysis</subject><subject>Surgery</subject><subject>Systematic review</subject><subject>Thyroid cancer</subject><subject>Thyroid gland</subject><subject>Thyroid nodules</subject><subject>Ultrasonic imaging</subject><subject>Ultrasound</subject><issn>1472-6823</issn><issn>1472-6823</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2022</creationdate><recordtype>article</recordtype><sourceid>PIMPY</sourceid><sourceid>DOA</sourceid><recordid>eNptkk2P1SAUhhujccarf8AViRs3HYGWFlyYTMavSSZxo2tyykeHmxYqtNf0R_kf5d5O1GsMIZDDex4Oh7coXhJ8RQhv3iRCBaYlpnkSzFnJHhWXpG5p2XBaPf5rf1E8S2mPMWk5xU-Li4rxuhKMXRY_3zvofUizUwiUWiKoFQWLJhgmmF3w6GBiWhJahjlCCovXZb84bTSyzhvkjdGDQZAmFzd958KUVmRDRHpju3QkjjC43oPPfOfRfL_G4DTyQS-DSW8RoLSm2YxwrCSagzM_EHiNRjNDCR6GNXOeF08sDMm8eFh3xbePH77efC7vvny6vbm-KxWr8VzWpOEtMG1JLVRLK14TXilMCWloS6q6sazDXINlinct000LBEBUxDLTqbaudsXtxtUB9nKKboS4ygBOngIh9hJiLnQw0nSVqjUoIbSocauhq6nlOdS0RlvOMuvdxpqWbjRaGZ8bOZxBz0-8u5d9OEhx_N0T4PUDIIbvi0mzHF1SZhjAm7AkSRtB6oY2VGTpq3-k-7DE3LxNxagQgv5R9ZAf4LwN-V51hMrrluCG4ir3a1dc_UeVhzajU8Eb63L8LIFuCSqGlKKxv99IsDwaVm6Gldmw8mRYyapfE7_f6Q</recordid><startdate>20220717</startdate><enddate>20220717</enddate><creator>Tarigan, Tri Juli Edi</creator><creator>Anwar, Budiman Syaeful</creator><creator>Sinto, Robert</creator><creator>Wisnu, Wismandari</creator><general>BioMed Central Ltd</general><general>BioMed Central</general><general>BMC</general><scope>AAYXX</scope><scope>CITATION</scope><scope>3V.</scope><scope>7QP</scope><scope>7TK</scope><scope>7X7</scope><scope>7XB</scope><scope>88E</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>AZQEC</scope><scope>BENPR</scope><scope>CCPQU</scope><scope>DWQXO</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>K9.</scope><scope>M0S</scope><scope>M1P</scope><scope>PIMPY</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>PRINS</scope><scope>7X8</scope><scope>5PM</scope><scope>DOA</scope></search><sort><creationdate>20220717</creationdate><title>Diagnostic accuracy of palpation versus ultrasound-guided fine needle aspiration biopsy for diagnosis of malignancy in thyroid nodules: a systematic review and meta-analysis</title><author>Tarigan, Tri Juli Edi ; Anwar, Budiman Syaeful ; Sinto, Robert ; Wisnu, Wismandari</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c540t-41687a5df149c72384183c02116271346f5b08daf5c8b75d67a1aa931f5ebc743</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2022</creationdate><topic>Accuracy</topic><topic>Analysis</topic><topic>Bias</topic><topic>Biopsy</topic><topic>Cancer</topic><topic>Cytology</topic><topic>Diagnosis</topic><topic>Endocrinology</topic><topic>Fine-needle aspiration biopsy</topic><topic>Grey literature</topic><topic>Histopathology</topic><topic>Malignancy</topic><topic>Meta-analysis</topic><topic>Nodules</topic><topic>Oncology, Experimental</topic><topic>Palpable versus USG guided</topic><topic>Patients</topic><topic>Practice guidelines (Medicine)</topic><topic>Researchers</topic><topic>Reviews</topic><topic>Software</topic><topic>Statistical analysis</topic><topic>Surgery</topic><topic>Systematic review</topic><topic>Thyroid cancer</topic><topic>Thyroid gland</topic><topic>Thyroid nodules</topic><topic>Ultrasonic imaging</topic><topic>Ultrasound</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Tarigan, Tri Juli Edi</creatorcontrib><creatorcontrib>Anwar, Budiman Syaeful</creatorcontrib><creatorcontrib>Sinto, Robert</creatorcontrib><creatorcontrib>Wisnu, Wismandari</creatorcontrib><collection>CrossRef</collection><collection>ProQuest Central (Corporate)</collection><collection>Calcium &amp; Calcified Tissue Abstracts</collection><collection>Neurosciences Abstracts</collection><collection>ProQuest - Health &amp; Medical Complete保健、医学与药学数据库</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>Medical Database (Alumni Edition)</collection><collection>Hospital Premium Collection</collection><collection>Hospital Premium Collection (Alumni Edition)</collection><collection>ProQuest Central (Alumni) (purchase pre-March 2016)</collection><collection>ProQuest Central (Alumni)</collection><collection>ProQuest Central</collection><collection>ProQuest Central Essentials</collection><collection>ProQuest Central</collection><collection>ProQuest One Community College</collection><collection>ProQuest Central Korea</collection><collection>Health Research Premium Collection</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>ProQuest Health &amp; Medical Complete (Alumni)</collection><collection>Health &amp; Medical Collection (Alumni Edition)</collection><collection>Medical Database</collection><collection>Publicly Available Content Database</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>ProQuest Central China</collection><collection>MEDLINE - Academic</collection><collection>PubMed Central (Full Participant titles)</collection><collection>Directory of Open Access Journals</collection><jtitle>BMC endocrine disorders</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Tarigan, Tri Juli Edi</au><au>Anwar, Budiman Syaeful</au><au>Sinto, Robert</au><au>Wisnu, Wismandari</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Diagnostic accuracy of palpation versus ultrasound-guided fine needle aspiration biopsy for diagnosis of malignancy in thyroid nodules: a systematic review and meta-analysis</atitle><jtitle>BMC endocrine disorders</jtitle><date>2022-07-17</date><risdate>2022</risdate><volume>22</volume><issue>1</issue><spage>1</spage><epage>181</epage><pages>1-181</pages><artnum>181</artnum><issn>1472-6823</issn><eissn>1472-6823</eissn><abstract>Thyroid nodule is a common health problem in endocrinology. Thyroid fine-needle aspiration biopsy (FNAB) cytology performed by palpation guided FNAB (PGFNAB) and ultrasound-guided FNAB (USGFNAB) are the preferred examinations for the diagnosis of thyroid cancer and part of the integration of the current thyroid nodule assessment. Although studies have shown USGFNAB to be more accurate than PGFNAB, inconsistencies from several studies and clinical guidelines still exist. The purpose of this study is to compare the diagnostic accuracy of Palpation versus Ultrasound-Guided Fine Needle Aspiration Biopsy in diagnosing malignancy of thyroid nodules. The systematic review and meta-analysis were prepared based on the PRISMA standards. Literature searches were carried out on three online databases (Pubmed/MEDLINE, Embase, and Proquest) and grey literatures. Data extraction was carried out manually from various studies that met the eligibility, followed by analysis to obtain pooled data on sensitivity, specificity, Diagnostic Odds Ratio (DOR) and Area Under Curve (AUC), and the comparison of the two methods. Total of 2517 articles were obtained, with 11 studies were included in this systematic review. The total sample was 2382, including 1128 subjects using PGFNAB and 1254 subjects using USGFNAB. The risk of bias was assessed using QUADAS-2 with mild-moderate results. The results of sensitivity, specificity, AUC and DOR in diagnosing thyroid nodules using PGFNAB were 76% (95% CI, 49–89%), 77% (95% CI, 56–95%), 0.827 and 11.6 (95% CI, 6–21) respectively. The results of sensitivity, specificity, AUC and DOR in diagnosing thyroid nodules using USGFNAB were 90% (95% CI, 81–95%), 80% (95% CI, 66–89%), 0.92 and 40 (95% CI, 23–69), respectively the results of the comparison test between PGFNAB and USGFNAB; Tsens USGFNAB of 0.99 ( p  = 0.023), AUC difference test of 0.093 ( p  = 0.000023). The diagnostic accuracy of USGFNAB is higher than PGFNAB in diagnosing malignancy of thyroid nodules. If it is accessible, the author recommends using USGFNAB as a diagnostic tool for thyroid nodules.</abstract><cop>London</cop><pub>BioMed Central Ltd</pub><pmid>35843955</pmid><doi>10.1186/s12902-022-01085-5</doi><oa>free_for_read</oa></addata></record>
fulltext fulltext
identifier ISSN: 1472-6823
ispartof BMC endocrine disorders, 2022-07, Vol.22 (1), p.1-181, Article 181
issn 1472-6823
1472-6823
language eng
recordid cdi_doaj_primary_oai_doaj_org_article_eb3c4dac99d9407dab42f8c4d67edf85
source Publicly Available Content Database; PubMed Central
subjects Accuracy
Analysis
Bias
Biopsy
Cancer
Cytology
Diagnosis
Endocrinology
Fine-needle aspiration biopsy
Grey literature
Histopathology
Malignancy
Meta-analysis
Nodules
Oncology, Experimental
Palpable versus USG guided
Patients
Practice guidelines (Medicine)
Researchers
Reviews
Software
Statistical analysis
Surgery
Systematic review
Thyroid cancer
Thyroid gland
Thyroid nodules
Ultrasonic imaging
Ultrasound
title Diagnostic accuracy of palpation versus ultrasound-guided fine needle aspiration biopsy for diagnosis of malignancy in thyroid nodules: a systematic review and meta-analysis
url http://sfxeu10.hosted.exlibrisgroup.com/loughborough?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-01-01T22%3A40%3A43IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-gale_doaj_&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Diagnostic%20accuracy%20of%20palpation%20versus%20ultrasound-guided%20fine%20needle%20aspiration%20biopsy%20for%20diagnosis%20of%20malignancy%20in%20thyroid%20nodules:%20a%20systematic%20review%20and%20meta-analysis&rft.jtitle=BMC%20endocrine%20disorders&rft.au=Tarigan,%20Tri%20Juli%20Edi&rft.date=2022-07-17&rft.volume=22&rft.issue=1&rft.spage=1&rft.epage=181&rft.pages=1-181&rft.artnum=181&rft.issn=1472-6823&rft.eissn=1472-6823&rft_id=info:doi/10.1186/s12902-022-01085-5&rft_dat=%3Cgale_doaj_%3EA710620318%3C/gale_doaj_%3E%3Cgrp_id%3Ecdi_FETCH-LOGICAL-c540t-41687a5df149c72384183c02116271346f5b08daf5c8b75d67a1aa931f5ebc743%3C/grp_id%3E%3Coa%3E%3C/oa%3E%3Curl%3E%3C/url%3E&rft_id=info:oai/&rft_pqid=2691529992&rft_id=info:pmid/35843955&rft_galeid=A710620318&rfr_iscdi=true