The Effect of Short-Term Consumption of Lactic Acid Bacteria on the Gut Microbiota in Obese People

Obesity is a problem of modern health care that causes the occurrence of many concomitant diseases: arterial hypertension, diabetes mellitus, non-alcoholic fatty liver disease, and cardiovascular diseases. New strategies for the treatment and prevention of obesity are being developed that are based...

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Bibliographic Details
Published in:Nutrients 2022-08, Vol.14 (16), p.3384
Main Authors: Burakova, Inna, Smirnova, Yuliya, Gryaznova, Mariya, Syromyatnikov, Mikhail, Chizhkov, Pavel, Popov, Evgeny, Popov, Vasily
Format: Article
Language:English
Subjects:
16S rRNA
Acids
Analysis
Bacteria
Bifidobacterium
Cardiovascular disease
Cardiovascular diseases
Care and treatment
Catenibacterium
Clostridium
Development and progression
Diabetes mellitus
Diabetes therapy
Diet therapy
Dietary supplements
digestive system
Faecalibacterium
Fatty liver
Gastrointestinal Microbiome
Gastrointestinal system
Health aspects
Health care
health services
Humans
Hypertension
Intestinal microflora
intestinal microorganisms
Lachnospiraceae
Lactic acid
Lactic acid bacteria
Lactobacillales
Lactobacilli
Lactobacillus
Lactobacillus acidophilus
Lactobacillus delbrueckii
Lactococcus
Limosilactobacillus fermentum
Liver diseases
Megasphaera
Metabolic disorders
Metabolism
microbiome
Microbiota
Microbiota (Symbiotic organisms)
Obesity
Obesity - microbiology
Obesity - therapy
Patient outcomes
people
Phascolarctobacterium
Physiological aspects
Probiotics
Probiotics - therapeutic use
Pseudobutyrivibrio
sequencing
Software
Statistical analysis
Streptococcus
Weight control
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Summary:Obesity is a problem of modern health care that causes the occurrence of many concomitant diseases: arterial hypertension, diabetes mellitus, non-alcoholic fatty liver disease, and cardiovascular diseases. New strategies for the treatment and prevention of obesity are being developed that are based on using probiotics for modulation of the gut microbiota. Our study aimed to evaluate the bacterial composition of the gut of obese patients before and after two weeks of lactic acid bacteria ( , , , and ) intake. The results obtained showed an increase in the number of members of the phylum Actinobacteriota in the group taking nutritional supplements, while the number of phylum Bacteroidota decreased in comparison with the control group. There has also been an increase in potentially beneficial groups: , , , , , , , , and . Along with this, a decrease in the genera was demonstrated: , , , , and , , , , and the group, which contribute to the development of various metabolic disorders. Modulation of the gut microbiota by lactic acid bacteria may be one of the ways to treat obesity.
ISSN:2072-6643
2072-6643
DOI:10.3390/nu14163384