Associations between "Cancer Risk", "Inflammation" and "Metabolic Syndrome": A Scoping Review

Individuals with metabolic syndrome exhibit simultaneously pro-thrombotic and pro-inflammatory conditions which more probably can lead to cardiovascular diseases progression, type 2 diabetes mellitus, and some types of cancer. The present scoping review is aimed at highlighting the association betwe...

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Bibliographic Details
Published in:Biology (Basel, Switzerland) Switzerland), 2024-05, Vol.13 (5), p.352
Main Authors: Vitale, Elsa, Rizzo, Alessandro, Santa, Kazuki, Jirillo, Emilio
Format: Article
Language:English
Subjects:
Adenocarcinoma
Adipocytes
Angiogenesis
B cells
Breast cancer
breast neoplasms
Cancer
cancer risk
Cardiovascular diseases
Cholesterol
Citation management software
Colorectal cancer
Colorectal carcinoma
colorectal neoplasms
Cytokines
Development and progression
Diabetes
Diabetes mellitus (non-insulin dependent)
Esophageal cancer
Esophageal carcinoma
Fatty acids
Health aspects
Hepatocellular carcinoma
hepatoma
High density lipoprotein
Hyperglycemia
Hypertension
Inflammation
Insulin resistance
Lipoproteins
Lymphocytes
Metabolic disorders
Metabolic syndrome
Metastasis
Nitric oxide
noninsulin-dependent diabetes mellitus
Obesity
oncogenesis
Oncology, Experimental
Oxidative stress
Physiology
Reviews
risk
Risk factors
Sedentary behavior
Tumor necrosis factor-TNF
Tumorigenesis
Type 2 diabetes
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Summary:Individuals with metabolic syndrome exhibit simultaneously pro-thrombotic and pro-inflammatory conditions which more probably can lead to cardiovascular diseases progression, type 2 diabetes mellitus, and some types of cancer. The present scoping review is aimed at highlighting the association between cancer risk, inflammation, and metabolic syndrome. A search strategy was performed, mixing keywords and MeSH terms, such as "Cancer Risk", "Inflammation", "Metabolic Syndrome", "Oncogenesis", and "Oxidative Stress", and matching them through Boolean operators. A total of 20 manuscripts were screened for the present study. Among the selected papers, we identified some associations with breast cancer, colorectal cancer, esophageal adenocarcinoma, hepatocellular carcinoma (HCC), and cancer in general. Cancer and its related progression may also depend also on a latent chronic inflammatory condition associated with other concomitant conditions, including type 2 diabetes mellitus, metabolic syndrome, and obesity. Therefore, prevention may potentially help individuals to protect themselves from cancer.
ISSN:2079-7737
2079-7737
DOI:10.3390/biology13050352