Synthesis and Neurotropic Activity of Novel Quinoline Derivatives

Hydroxyalkyl and carboxyalkyl derivatives of silatetrahydroisoquinoline, tetrahydroisoquinoline and tetrahydroquinoline have been synthesized. Their neurotropic activity has been investigated.

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Bibliographic Details
Published in:Molecules (Basel, Switzerland) Switzerland), 1997-01, Vol.2 (12), p.180-185
Main Authors: Lukevics, Edmunds, Segal, Izolda, Zablotskaya, Alla, Germane, Skaidrite
Format: Article
Language:English
Subjects:
Amino acids
Ethanol
Hypoxia
neurotropic activity
Silatetrahydroquinoline
tetrahydroquinolyl amino acids
trialkylsiloxyethylisoquinolines
Vacuum distillation
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Description
Summary:Hydroxyalkyl and carboxyalkyl derivatives of silatetrahydroisoquinoline, tetrahydroisoquinoline and tetrahydroquinoline have been synthesized. Their neurotropic activity has been investigated.
ISSN:1420-3049
1420-3049
DOI:10.3390/21200180