Physiological and prognostic differences between types of exercise stress echocardiography for functional mitral regurgitation

ObjectiveSecondary mitral regurgitation (MR) demonstrates dynamic change during exercise. This prospective observational study aimed to compare exercise stress echocardiography (ESE) where handgrip exercise (handgrip-ESE) or semisupine ergometer exercise was performed (ergometer-ESE) for patients wi...

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Bibliographic Details
Published in:Open heart 2021-04, Vol.8 (1), p.e001583
Main Authors: Kagiyama, Nobuyuki, Toki, Misako, Yuri, Takuya, Aritaka, Shingo, Hayashida, Akihiro, Sengupta, Partho P, Yoshida, Kiyoshi
Format: Article
Language:English
Subjects:
Blood pressure
Clinical medicine
echocardiography
Heart failure
mitral valve insufficiency
Patients
Peptides
Physiology
Pulmonary arteries
Survival analysis
Valvular Heart Disease
Workloads
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Summary:ObjectiveSecondary mitral regurgitation (MR) demonstrates dynamic change during exercise. This prospective observational study aimed to compare exercise stress echocardiography (ESE) where handgrip exercise (handgrip-ESE) or semisupine ergometer exercise was performed (ergometer-ESE) for patients with secondary MR.MethodsHandgrip-ESE and symptom-limited ergometer-ESE were performed for 53 patients (median age (IQR): 68 (58–78) years; 70% male) on the same day. Baseline global longitudinal strain (GLS) was 9.2% (6.0%–14.0%) and MR volume was 20 (14–26) mL. All-cause death and cardiac hospitalisation were tracked for median 439 (101–507) days.ResultsHandgrip-ESE induced slightly but significantly greater degrees of MR increase (median one grade increase; p
ISSN:2053-3624
2398-595X
2053-3624
DOI:10.1136/openhrt-2021-001583