Is Takotsubo syndrome induced by patent ductus arteriosus occlusion?

• Published in: BMC cardiovascular disorders 2024-03, Vol.24 (1), p.135-7, Article 135
• Main Authors: Li, Shuhao, Yang, Senyan, Zhou, Shujing, Zhang, Shuang, Li, Xueying, Zhang, Haibo, Ren, Ping, Liu, Yanwu, Liu, Ying, Chen, Yuanguo
• Format: Article
• Language: English
• Subjects: Autonomic nervous system; Beta blockers; Blood pressure; Cardiac arrhythmia; Cardiac catheterization; Cardiovascular disease; Care and treatment; Catheters; Complications and side effects; Congenital heart disease; Congestive heart failure; Coronary vessels; Diagnosis; Ductus Arteriosus, Patent - complications; Ejection fraction; Electrocardiography; Emotions; Estrogens; Female; Genetic factors; Heart diseases; Heart failure; Heart Failure - complications; Heart rate; Hemodynamics; Humans; Inflammation; Interventional occlusion; case report; Intubation; Medical imaging; Middle Aged; Nervous system; Pain; Parasympathetic nervous system; Patent ductus arteriosus; Pathogenesis; Patients; Primary care; Pulmonary arteries; Risk factors; Syndrome; Takotsubo Cardiomyopathy - diagnostic imaging; Takotsubo Cardiomyopathy - etiology; Takotsubo syndrome; Vein & artery diseases
• ISSN: 1471-2261; 1471-2261
• DOI: 10.1186/s12872-024-03788-0

Takotsubo syndrome (TTS), commonly referred to as "broken heart syndrome," is a distinctive form of acute and reversible heart failure that primarily affects young to middle-aged individuals, particularly women. While emotional or physical stressors often trigger TTS, rare cases have been linked to interventional procedures for congenital heart disease (CHD). Despite its recognition, the exact causes of TTS remain elusive. Research indicates that dysregulation in autonomic nerve function, involving sympathetic and parasympathetic activities, plays a pivotal role. Genetic factors, hormonal influences like estrogen, and inflammatory processes also contribute, unveiling potential gender-specific differences in its occurrence. Understanding these multifaceted aspects of TTS is crucial for refining clinical approaches and therapies. Continued research efforts will not only deepen our understanding of this syndrome but also pave the way for more targeted and effective diagnostic and treatment strategies. In this report, we conduct an in-depth analysis of a case involving a TTS patient, examining the illness progression and treatment procedures. The aim of this analysis is to enhance the understanding of TTS among primary care physicians. By delving into this case, we aspire to prevent misdiagnosis of typical TTS cases that patients may present, thereby ensuring a more accurate diagnosis and appropriate treatment.