Surgical Treatment of Lithiasis of the Main Pancreatic Duct: A Challenging Case and a Literature Review

• Published in: Diseases 2024-05, Vol.12 (5), p.86
• Main Authors: Brebu, Dan, Prodan-Bărbulescu, Cătălin, Braicu, Vlad, Pașca, Paul, Borcean, George, Florea, Sabrina, Bîrlog, Clarisa, Dobrescu, Amadeus, Cornianu, Mărioara, Lazăr, Fulger, Totolici, Bogdan, Duță, Ciprian, Faur, Flaviu Ionuț
• Format: Article
• Language: English
• Subjects: Abdomen; Anastomosis; Bile ducts; Care and treatment; Case studies; Classification; Comparative analysis; Complications and side effects; Connective tissue; corporeo-caudal pancreatectomy; Development and progression; Diagnosis; Endoscopy; Enzymes; Extracorporeal shockwave lithotripsy; Health aspects; Implants; Inflammation; Literature reviews; Lithiasis; lithiasis of main pancreatic duct; Lithotripsy; Lymphatic system; Metabolism; Pancreas; pancreas duct stone; Pancreatectomy; pancreatic calculi; pancreaticolithiasis; Pancreatitis; Parenchyma; Small intestine; Standardization; Surgery; Therapeutic applications; Ultrasonic imaging; Veins & arteries; Wirsung lithiasis
• ISSN: 2079-9721; 2079-9721
• DOI: 10.3390/diseases12050086

Pancreaticolithiasis represents a rare phenomenon, being superimposed most of the time on a form of chronic pancreatitis of multifactorial etiology. Pancreaticolithiasis is a late complication of the phenomenon of chronic pancreatitis. The reverberant inflammatory process, followed by the fibrotic degeneration of the pancreatic parenchyma, and pancreatic fluid stasis at the ductal level are factors that contribute to the phenomenon of calcium precipitation. This article describes the case of a patient with a diagnosis of pancreaticolithiasis (Wirsung duct lithiasis), a phenomenon superimposed on chronic pancreatitis of ethanolic cause (Rosemont classification). It was decided to perform surgery via the classical approach with the perfection of corporeo-caudal pancreatectomy and preservation of the splenic vessels (Kimura procedure) with pancreatico-jejunal anastomosis on the Roux-en-Y loop. The aim of this study is to identify the best method of treatment for pancreaticolithiasis. To enhance the case and provide a basis for standardization, a literature review was carried out, which included a total of six articles. The results of this study highlight that, currently, the management of symptomatic pancreaticolithiasis encompasses medical therapy (enzyme replacement therapy), interventional therapy (ESWL (extracorporeal shock wave lithotripsy) ± ERCP (endoscopic retrograde cholangiopancreatography), ERCP + sphincterotomy + stent insertion, and POP (oral pancreatoscopy)), and surgical treatment. In conclusion, based on the analysis conducted in this study, the size of the calculi present determines which is the suitable therapeutic care. Unlike stones over 0.5 cm, when surgery is explicitly advised for therapeutic purposes in the absence of endoscopic techniques, stones under 0.5 cm should be treated using endoscopic procedures.