Effect of lactoferrin on enamel characteristics of primary and permanent teeth: an in-vitro study

Lactoferrin, a glycoprotein naturally found in breast milk, is known for its bactericidal and antiviral properties, as well as its capacity to modulate the immune system; therefore, pediatricians routinely recommend it as dietary support. The objective of this study was to determine how lactoferrin...

Full description

Saved in:
Bibliographic Details
Published in:BMC oral health 2023-12, Vol.23 (1), p.993-993, Article 993
Main Authors: Atia, Nouran Samir Mohamed, El-Nemr, Reham Ahmed, Abo-Elsoud, Asmaa Ali Emam
Format: Article
Language:English
Subjects:
Antiviral activity
Antiviral agents
Breast milk
Care and treatment
Dental enamel
Dental erosion
Dentistry
Dentition
Enamel
Enamel and enameling
Evaluation
Hardness
Health aspects
Immune system
Influence
Iron
Lactoferrin
Lactoferrins
Maxillofacial surgery
Milk
Molars
Oral health
Oral medication
Pediatrics
Phosphorus
Physiology
Premolars
Saliva
Sample size
Software
Statistical analysis
Teeth
Weight
Citations: Items that this one cites
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Lactoferrin, a glycoprotein naturally found in breast milk, is known for its bactericidal and antiviral properties, as well as its capacity to modulate the immune system; therefore, pediatricians routinely recommend it as dietary support. The objective of this study was to determine how lactoferrin oral suspension could affect the enamel surface characteristics of primary and permanent teeth. This research was conducted on 40 unidentified extracted teeth, including primary and permanent teeth. Experimental teeth were free of cracks or enamel defects, as confirmed by careful examination using a dental operating microscope. The crowns were bisected into 80 specimens and assorted into two groups based on the type of dentition. Group DM included 40 specimens of second deciduous molars, while Group PM contained 40 samples of first premolars. Each of the DM and PM specimens was subsequently split based on the type of dispersion medium into two subgroups: a control subgroup (artificial saliva) and a test subgroup (lactoferrin suspension). The specimens were immersed in lactoferrin suspension for two minutes, then kept in artificial saliva for the rest of the 24 h for 30 successive days. This is a pioneering study about the effect of orally supplemented lactoferrin on teeth; therefore, we examined enamel hardness, ultra-morphology, and mineral contents. Our findings indicated a highly significant decrease (p 
ISSN:1472-6831
1472-6831
DOI:10.1186/s12903-023-03709-1