Induction and assessment of persistent radioresistance in murine leukocytes in vivo

The aim of the present study was to investigate whether weekly exposure to gamma rays causes a persistent increase in the number of radioresistant leukocytes in mice in vivo. Using the comet assay, 1 Gy radiation exposure decreased the percentage of leukocytes with less than 5% DNA in the tail (

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Bibliographic Details
Published in:Biochemistry and biophysics reports 2022-09, Vol.31, p.101296-101296, Article 101296
Main Authors: Morales-Ramírez, Pedro, Cruz-Vallejo, Virginia, Vallarino-Kelly, Teresita, Rodríguez-Reyes, Regina, González-Beltrán, Francisco
Format: Article
Language:English
Subjects:
Comet assay
Gamma rays
Mutation selection
Radioresistance
Stem cells
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Description
Summary:The aim of the present study was to investigate whether weekly exposure to gamma rays causes a persistent increase in the number of radioresistant leukocytes in mice in vivo. Using the comet assay, 1 Gy radiation exposure decreased the percentage of leukocytes with less than 5% DNA in the tail (
ISSN:2405-5808
2405-5808
DOI:10.1016/j.bbrep.2022.101296