Zieve Syndrome: A Clinical Triad, or Perchance a Quartet?

Zieve syndrome presents with a triad of hemolytic anemia, unexplained jaundice, and hyperlipidemia secondary to alcohol use/alcohol-induced liver injury, highlighting hemolytic anemia as the hallmark feature. Zieve syndrome is more common than originally perceived as its incidence is estimated to be...

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Bibliographic Details
Published in:JIM - high impact case reports 2022, Vol.10, p.23247096221121393-23247096221121393
Main Authors: Reyes, Jonathan Vincent M., Ahmad, Saad, Majeed, Hafsa, Kandoth, Eugenio, Lieber, Joseph J.
Format: Article
Language:English
Subjects:
Case Report
Case reports
Gastroenterology
Liver
Medical diagnosis
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Summary:Zieve syndrome presents with a triad of hemolytic anemia, unexplained jaundice, and hyperlipidemia secondary to alcohol use/alcohol-induced liver injury, highlighting hemolytic anemia as the hallmark feature. Zieve syndrome is more common than originally perceived as its incidence is estimated to be 1 in 1600 admissions, but its mechanism is still poorly understood. This is a case of a 29-year-old man who developed Zieve syndrome shortly after admission for pancreatitis secondary to alcohol use disorder. Early diagnosis is important to reduce unnecessary tests and interventions. Further studies should be considered to evaluate the association between Zieve syndrome and pancreatitis.
ISSN:2324-7096
2324-7096
DOI:10.1177/23247096221121393