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Chemical composition, antioxidant and antibacterial properties of Achillea collina Becker ex Heimerl s.l. and A. pannonica Scheele essential oils
The in vitro antioxidant and antimicrobial activities of two Achillea millefolium (Adanson) Koch s.l species essential oils (A. collina Becker ex Heimerl s.l. and A. pannonica Scheele, Asteraceae) originating from the Golija and Radan mountains (Serbia) were investigated. The chemical profiles of th...
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Published in: | Molecules (Basel, Switzerland) Switzerland), 2008-09, Vol.13 (9), p.2058-2068 |
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description | The in vitro antioxidant and antimicrobial activities of two Achillea millefolium (Adanson) Koch s.l species essential oils (A. collina Becker ex Heimerl s.l. and A. pannonica Scheele, Asteraceae) originating from the Golija and Radan mountains (Serbia) were investigated. The chemical profiles of the essential oils were evaluated by GC-MS. Antioxidant activity was assessed as free radical scavenging capacity (RSC) towards 2,2-diphenyl-1-picrylhydrazil (DPPH) radicals, together with effects on lipid peroxidation (LP). Antibacterial activity was examined on 21 bacterial strains. Based on the chemical composition of the essential oil, A. collina s.l. from Mount Golija was classified as a chamazulene chemotype (tetraploid). The high percentage of oxygenated monoterpenes and absence of azulene in the essential oil obtained from A. pannonica from Radan pointing that this population is octaploid. Essential oil of A. pannonica expressed stronger antimicrobial activity on almost all tested bacteria. Furthermore, this essential oil expressed higher scavenging effects on DPPH radical (IC(50) = 0.52 comparing to 0.62 mug/mL). Only in the LP evaluation, essential oil of A. collina s.l. from Golija exhibited stronger antioxidant activity (IC(50) = 0.75 comparing to 2.12 mug/mL). |
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The chemical profiles of the essential oils were evaluated by GC-MS. Antioxidant activity was assessed as free radical scavenging capacity (RSC) towards 2,2-diphenyl-1-picrylhydrazil (DPPH) radicals, together with effects on lipid peroxidation (LP). Antibacterial activity was examined on 21 bacterial strains. Based on the chemical composition of the essential oil, A. collina s.l. from Mount Golija was classified as a chamazulene chemotype (tetraploid). The high percentage of oxygenated monoterpenes and absence of azulene in the essential oil obtained from A. pannonica from Radan pointing that this population is octaploid. Essential oil of A. pannonica expressed stronger antimicrobial activity on almost all tested bacteria. Furthermore, this essential oil expressed higher scavenging effects on DPPH radical (IC(50) = 0.52 comparing to 0.62 mug/mL). Only in the LP evaluation, essential oil of A. collina s.l. from Golija exhibited stronger antioxidant activity (IC(50) = 0.75 comparing to 2.12 mug/mL).</description><identifier>ISSN: 1420-3049</identifier><identifier>EISSN: 1420-3049</identifier><identifier>DOI: 10.3390/molecules13092058</identifier><identifier>PMID: 18830141</identifier><language>eng</language><publisher>Switzerland: MDPI AG</publisher><subject>Achillea - chemistry ; Achillea - classification ; Achillea millefolium s.l ; Anti-Bacterial Agents - chemistry ; Anti-Bacterial Agents - pharmacology ; Antimicrobial ; Antimicrobial agents ; Antioxidant ; Antioxidants ; Antioxidants - chemistry ; Antioxidants - pharmacology ; Biphenyl Compounds - chemistry ; Chemotypes ; Essential oil ; Geography ; Hydrazines - chemistry ; Hydrocarbons ; Investigations ; Lipid Peroxidation - drug effects ; Medicine ; Microbial Sensitivity Tests ; Oils & fats ; Oils, Volatile - chemistry ; Oils, Volatile - pharmacology ; Oxidation-Reduction - drug effects ; Pharmacy ; Picrates ; Plant Oils - chemistry ; Plant Oils - pharmacology ; Serbia ; Species Specificity ; Staphylococcus aureus - drug effects ; Streptococcus pneumoniae - drug effects</subject><ispartof>Molecules (Basel, Switzerland), 2008-09, Vol.13 (9), p.2058-2068</ispartof><rights>Copyright MDPI AG 2008</rights><rights>2008 by the authors. 2008</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c491t-9a277d82fdef4bd98a3d049762649fae0f437d0167b2895889c3a9567428a8643</citedby><cites>FETCH-LOGICAL-c491t-9a277d82fdef4bd98a3d049762649fae0f437d0167b2895889c3a9567428a8643</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.proquest.com/docview/1531128824/fulltextPDF?pq-origsite=primo$$EPDF$$P50$$Gproquest$$Hfree_for_read</linktopdf><linktohtml>$$Uhttps://www.proquest.com/docview/1531128824?pq-origsite=primo$$EHTML$$P50$$Gproquest$$Hfree_for_read</linktohtml><link.rule.ids>230,314,727,780,784,885,25753,27924,27925,37012,37013,44590,53791,53793,75126</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/18830141$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Bozin, Biljana</creatorcontrib><creatorcontrib>Mimica-Dukic, Neda</creatorcontrib><creatorcontrib>Bogavac, Mirjana</creatorcontrib><creatorcontrib>Suvajdzic, Ljiljana</creatorcontrib><creatorcontrib>Simin, Natasa</creatorcontrib><creatorcontrib>Samojlik, Isidora</creatorcontrib><creatorcontrib>Couladis, Maria</creatorcontrib><title>Chemical composition, antioxidant and antibacterial properties of Achillea collina Becker ex Heimerl s.l. and A. pannonica Scheele essential oils</title><title>Molecules (Basel, Switzerland)</title><addtitle>Molecules</addtitle><description>The in vitro antioxidant and antimicrobial activities of two Achillea millefolium (Adanson) Koch s.l species essential oils (A. collina Becker ex Heimerl s.l. and A. pannonica Scheele, Asteraceae) originating from the Golija and Radan mountains (Serbia) were investigated. The chemical profiles of the essential oils were evaluated by GC-MS. Antioxidant activity was assessed as free radical scavenging capacity (RSC) towards 2,2-diphenyl-1-picrylhydrazil (DPPH) radicals, together with effects on lipid peroxidation (LP). Antibacterial activity was examined on 21 bacterial strains. Based on the chemical composition of the essential oil, A. collina s.l. from Mount Golija was classified as a chamazulene chemotype (tetraploid). The high percentage of oxygenated monoterpenes and absence of azulene in the essential oil obtained from A. pannonica from Radan pointing that this population is octaploid. Essential oil of A. pannonica expressed stronger antimicrobial activity on almost all tested bacteria. Furthermore, this essential oil expressed higher scavenging effects on DPPH radical (IC(50) = 0.52 comparing to 0.62 mug/mL). Only in the LP evaluation, essential oil of A. collina s.l. from Golija exhibited stronger antioxidant activity (IC(50) = 0.75 comparing to 2.12 mug/mL).</description><subject>Achillea - chemistry</subject><subject>Achillea - classification</subject><subject>Achillea millefolium s.l</subject><subject>Anti-Bacterial Agents - chemistry</subject><subject>Anti-Bacterial Agents - pharmacology</subject><subject>Antimicrobial</subject><subject>Antimicrobial agents</subject><subject>Antioxidant</subject><subject>Antioxidants</subject><subject>Antioxidants - chemistry</subject><subject>Antioxidants - pharmacology</subject><subject>Biphenyl Compounds - chemistry</subject><subject>Chemotypes</subject><subject>Essential oil</subject><subject>Geography</subject><subject>Hydrazines - chemistry</subject><subject>Hydrocarbons</subject><subject>Investigations</subject><subject>Lipid Peroxidation - drug effects</subject><subject>Medicine</subject><subject>Microbial Sensitivity Tests</subject><subject>Oils & fats</subject><subject>Oils, Volatile - chemistry</subject><subject>Oils, Volatile - pharmacology</subject><subject>Oxidation-Reduction - drug effects</subject><subject>Pharmacy</subject><subject>Picrates</subject><subject>Plant Oils - chemistry</subject><subject>Plant Oils - pharmacology</subject><subject>Serbia</subject><subject>Species Specificity</subject><subject>Staphylococcus aureus - drug effects</subject><subject>Streptococcus pneumoniae - drug effects</subject><issn>1420-3049</issn><issn>1420-3049</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2008</creationdate><recordtype>article</recordtype><sourceid>PIMPY</sourceid><sourceid>DOA</sourceid><recordid>eNplkttu1DAQhiNERUvhAbhBlpC4Yhef4tg3SMsKaKVKvQCuLceedL04cbATVB6DN8Z7ED1wNePxP9_4t6aqXhG8ZEzh930MYOcAmTCsKK7lk-qMcIoXDHP19F5-Wj3PeYsxJZzUz6pTIiXDJT-r_qw30HtrArKxH2P2k4_DO2SGEm-9K7Hkbn9ujZ0g-SIdUxwhTR4yih1a2Y0PAUwhhOAHgz6C_QEJwS26AN9DCigvw3LPWS3RaIYhDmUk-mo3AAEQ5AyFX8DRh_yiOulMyPDyGM-r758_fVtfLK6uv1yuV1cLyxWZFsrQpnGSdg463jolDXPFaSOo4KozgDvOGoeJaFoqVS2lssyoWjScSiMFZ-fV5YHrotnqMfnepN86Gq_3hZhutCkebQAN1igJjAM0jHeNVZS2oJilonW8k6KwPhxY49z24Gyxk0x4AH14M_iNvom_tKC8Jg0rgLdHQIo_Z8iT7n22EIIZIM5ZCyWIovVu0ptHwm2c01A-SpOaEUKlpDtv5KCyKeacoPv3FIL1bnX0f6tTel7f93DXcdwV9hfGt8Oo</recordid><startdate>20080902</startdate><enddate>20080902</enddate><creator>Bozin, Biljana</creator><creator>Mimica-Dukic, Neda</creator><creator>Bogavac, Mirjana</creator><creator>Suvajdzic, Ljiljana</creator><creator>Simin, Natasa</creator><creator>Samojlik, Isidora</creator><creator>Couladis, Maria</creator><general>MDPI AG</general><general>MDPI</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>3V.</scope><scope>7X7</scope><scope>7XB</scope><scope>88E</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>AZQEC</scope><scope>BENPR</scope><scope>CCPQU</scope><scope>DWQXO</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>K9.</scope><scope>M0S</scope><scope>M1P</scope><scope>PIMPY</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>PRINS</scope><scope>7X8</scope><scope>5PM</scope><scope>DOA</scope></search><sort><creationdate>20080902</creationdate><title>Chemical composition, antioxidant and antibacterial properties of Achillea collina Becker ex Heimerl s.l. and A. pannonica Scheele essential oils</title><author>Bozin, Biljana ; Mimica-Dukic, Neda ; Bogavac, Mirjana ; Suvajdzic, Ljiljana ; Simin, Natasa ; Samojlik, Isidora ; Couladis, Maria</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c491t-9a277d82fdef4bd98a3d049762649fae0f437d0167b2895889c3a9567428a8643</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2008</creationdate><topic>Achillea - chemistry</topic><topic>Achillea - classification</topic><topic>Achillea millefolium s.l</topic><topic>Anti-Bacterial Agents - chemistry</topic><topic>Anti-Bacterial Agents - pharmacology</topic><topic>Antimicrobial</topic><topic>Antimicrobial agents</topic><topic>Antioxidant</topic><topic>Antioxidants</topic><topic>Antioxidants - chemistry</topic><topic>Antioxidants - pharmacology</topic><topic>Biphenyl Compounds - chemistry</topic><topic>Chemotypes</topic><topic>Essential oil</topic><topic>Geography</topic><topic>Hydrazines - chemistry</topic><topic>Hydrocarbons</topic><topic>Investigations</topic><topic>Lipid Peroxidation - drug effects</topic><topic>Medicine</topic><topic>Microbial Sensitivity Tests</topic><topic>Oils & fats</topic><topic>Oils, Volatile - chemistry</topic><topic>Oils, Volatile - pharmacology</topic><topic>Oxidation-Reduction - drug effects</topic><topic>Pharmacy</topic><topic>Picrates</topic><topic>Plant Oils - chemistry</topic><topic>Plant Oils - pharmacology</topic><topic>Serbia</topic><topic>Species Specificity</topic><topic>Staphylococcus aureus - drug effects</topic><topic>Streptococcus pneumoniae - drug effects</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Bozin, Biljana</creatorcontrib><creatorcontrib>Mimica-Dukic, Neda</creatorcontrib><creatorcontrib>Bogavac, Mirjana</creatorcontrib><creatorcontrib>Suvajdzic, Ljiljana</creatorcontrib><creatorcontrib>Simin, Natasa</creatorcontrib><creatorcontrib>Samojlik, Isidora</creatorcontrib><creatorcontrib>Couladis, Maria</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>ProQuest Central (Corporate)</collection><collection>ProQuest Health and Medical</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>Medical Database (Alumni Edition)</collection><collection>Hospital Premium Collection</collection><collection>Hospital Premium Collection (Alumni Edition)</collection><collection>ProQuest Central (Alumni) (purchase pre-March 2016)</collection><collection>ProQuest Central (Alumni)</collection><collection>ProQuest Central</collection><collection>ProQuest Central Essentials</collection><collection>AUTh Library subscriptions: ProQuest Central</collection><collection>ProQuest One Community College</collection><collection>ProQuest Central Korea</collection><collection>Health Research Premium Collection</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>Health & Medical Collection (Alumni Edition)</collection><collection>PML(ProQuest Medical Library)</collection><collection>ProQuest - Publicly Available Content Database</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>ProQuest Central China</collection><collection>MEDLINE - Academic</collection><collection>PubMed Central (Full Participant titles)</collection><collection>DOAJ Directory of Open Access Journals</collection><jtitle>Molecules (Basel, Switzerland)</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Bozin, Biljana</au><au>Mimica-Dukic, Neda</au><au>Bogavac, Mirjana</au><au>Suvajdzic, Ljiljana</au><au>Simin, Natasa</au><au>Samojlik, Isidora</au><au>Couladis, Maria</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Chemical composition, antioxidant and antibacterial properties of Achillea collina Becker ex Heimerl s.l. and A. pannonica Scheele essential oils</atitle><jtitle>Molecules (Basel, Switzerland)</jtitle><addtitle>Molecules</addtitle><date>2008-09-02</date><risdate>2008</risdate><volume>13</volume><issue>9</issue><spage>2058</spage><epage>2068</epage><pages>2058-2068</pages><issn>1420-3049</issn><eissn>1420-3049</eissn><abstract>The in vitro antioxidant and antimicrobial activities of two Achillea millefolium (Adanson) Koch s.l species essential oils (A. collina Becker ex Heimerl s.l. and A. pannonica Scheele, Asteraceae) originating from the Golija and Radan mountains (Serbia) were investigated. The chemical profiles of the essential oils were evaluated by GC-MS. Antioxidant activity was assessed as free radical scavenging capacity (RSC) towards 2,2-diphenyl-1-picrylhydrazil (DPPH) radicals, together with effects on lipid peroxidation (LP). Antibacterial activity was examined on 21 bacterial strains. Based on the chemical composition of the essential oil, A. collina s.l. from Mount Golija was classified as a chamazulene chemotype (tetraploid). The high percentage of oxygenated monoterpenes and absence of azulene in the essential oil obtained from A. pannonica from Radan pointing that this population is octaploid. Essential oil of A. pannonica expressed stronger antimicrobial activity on almost all tested bacteria. Furthermore, this essential oil expressed higher scavenging effects on DPPH radical (IC(50) = 0.52 comparing to 0.62 mug/mL). Only in the LP evaluation, essential oil of A. collina s.l. from Golija exhibited stronger antioxidant activity (IC(50) = 0.75 comparing to 2.12 mug/mL).</abstract><cop>Switzerland</cop><pub>MDPI AG</pub><pmid>18830141</pmid><doi>10.3390/molecules13092058</doi><tpages>11</tpages><oa>free_for_read</oa></addata></record> |
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subjects | Achillea - chemistry Achillea - classification Achillea millefolium s.l Anti-Bacterial Agents - chemistry Anti-Bacterial Agents - pharmacology Antimicrobial Antimicrobial agents Antioxidant Antioxidants Antioxidants - chemistry Antioxidants - pharmacology Biphenyl Compounds - chemistry Chemotypes Essential oil Geography Hydrazines - chemistry Hydrocarbons Investigations Lipid Peroxidation - drug effects Medicine Microbial Sensitivity Tests Oils & fats Oils, Volatile - chemistry Oils, Volatile - pharmacology Oxidation-Reduction - drug effects Pharmacy Picrates Plant Oils - chemistry Plant Oils - pharmacology Serbia Species Specificity Staphylococcus aureus - drug effects Streptococcus pneumoniae - drug effects |
title | Chemical composition, antioxidant and antibacterial properties of Achillea collina Becker ex Heimerl s.l. and A. pannonica Scheele essential oils |
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