Correlation of TNF-α, IFN-γ and TGF-β Expression with In-vitro Fertilization Success Rates in Women with Recurrent Implantation Failure Undergoing Treatment with Intra-lipid Infusion

This study aimed at assessing the correlations between gene expression of TNF-α, IFN-γ, TGF-β in peripheral lymphocytes from women suffering from repeated implantation failure before and after intravenous Intra-lipid (IL) therapy, and correlation between changes in gene expression with IL infusion a...

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Bibliographic Details
Published in:Journal of pure & applied microbiology : an international research journal of microbiology 2022-06, Vol.16 (2), p.1307-1317
Main Authors: Harby, Islam Khaled Ali, Ahmed, Ola Ibrahim, Zaki, Wafaa K., Faris, Mohammed Ahmed, El-Deen, Noha Nagi Salah
Format: Article
Language:English
Subjects:
ifn-γ
intralipid therapy
ivf failure
tgf-β
tnf-α
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Summary:This study aimed at assessing the correlations between gene expression of TNF-α, IFN-γ, TGF-β in peripheral lymphocytes from women suffering from repeated implantation failure before and after intravenous Intra-lipid (IL) therapy, and correlation between changes in gene expression with IL infusion and success rate of IVF cycles. Twenty-three women complaining of unexplained infertility without history of autoimmune disorders, or immunodeficient diseases were included. All women included aged
ISSN:0973-7510
2581-690X
DOI:10.22207/JPAM.16.2.59