Patterns of Antihypertensive Drug Utilization among US Adults with Diabetes and Comorbid Hypertension: The National Health and Nutrition Examination Survey 1999-2014

Background: Diabetes and hypertension are the 2 leading risk factors for suboptimal cardiovascular and renal outcomes. These 2 conditions often coexist and can benefit from antihypertensive therapy, which may lead to blood pressure control and reduced risk for nephropathy (as evidenced by albuminuri...

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Bibliographic Details
Published in:Clinical Medicine Insights. Cardiology 2019, Vol.13, p.1179546819839418
Main Authors: Gu, Anna, Farzadeh, Shireen N, Chang, You Jin, Kwong, Andrew, Lam, Sum
Format: Article
Language:English
Subjects:
Adults
Age
Angina pectoris
Antihypertensives
Blood pressure
Cardiovascular disease
Comorbidity
Diabetes
Diuretics
Educational attainment
Enzymes
Ethnicity
Heart attacks
Heart failure
Hypertension
Kidney diseases
Mortality
Original Research
Patients
Population
Studies
Trends
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Summary:Background: Diabetes and hypertension are the 2 leading risk factors for suboptimal cardiovascular and renal outcomes. These 2 conditions often coexist and can benefit from antihypertensive therapy, which may lead to blood pressure control and reduced risk for nephropathy (as evidenced by albuminuria). Objective: To quantify the trends of antihypertensive drug use and to assess the impact of antihypertensive treatment on the prevalence of blood pressure control and albuminuria, among US adults with coexisting diabetes and hypertension. Methods: In this serial cross-sectional study, we analyzed data from the 1999-2014 National Health and Nutrition Examination Survey (N = 3586). We determine the prevalence of antihypertensive use, drug classes used, and their association with blood pressure control and albuminuria. Results: During the study period, the study population experienced substantial increase in antihypertensive treatment (from 84.6% in 1999-2002 to 90.1% in 2011-2014, Ptrend 
ISSN:1179-5468
1179-5468
DOI:10.1177/1179546819839418