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Conditional cash transfers and mortality in people hospitalised with psychiatric disorders: A cohort study of the Brazilian Bolsa Família Programme
Psychiatric patients experience lower life expectancy compared to the general population. Conditional cash transfer programmes (CCTPs) have shown promise in reducing mortality rates, but their impact on psychiatric patients has been unclear. This study tests the association between being a Brazilian...
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Published in: | PLoS medicine 2024-12, Vol.21 (12), p.e1004486 |
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description | Psychiatric patients experience lower life expectancy compared to the general population. Conditional cash transfer programmes (CCTPs) have shown promise in reducing mortality rates, but their impact on psychiatric patients has been unclear. This study tests the association between being a Brazilian Bolsa Família Programme (BFP) recipient and the risk of mortality among people previously hospitalised with any psychiatric disorders.
This cohort study utilised Brazilian administrative datasets, linking social and health system data from the 100 Million Brazilian Cohort, a population-representative study. We followed individuals who applied for BFP following a single hospitalisation with a psychiatric disorder between 2008 and 2015. The outcome was mortality and specific causes, defined according to International Classification of Diseases 10th Revision (ICD-10). Cox proportional hazards models estimated the hazard ratio (HR) for overall mortality and competing risks models estimated the HR for specific causes of death, both associated with being a BFP recipient, adjusted for confounders, and weighted with a propensity score. We included 69,901 psychiatric patients aged between 10 and 120, with the majority being male (60.5%), and 26,556 (37.99%) received BFP following hospitalisation. BFP was associated with reduced overall mortality (HR 0.93, 95% CI 0.87,0.98, p 0.018) and mortality due to natural causes (HR 0.89, 95% CI 0.83, 0.96, p < 0.001). Reduction in suicide (HR 0.90, 95% CI 0.68, 1.21, p = 0.514) was observed, although it was not statistically significant. The BFP's effects on overall mortality were more pronounced in females and younger individuals. In addition, 4% of deaths could have been prevented if BFP had been present (population attributable risk (PAF) = 4%, 95% CI 0.06, 7.10).
BFP appears to reduce mortality rates among psychiatric patients. While not designed to address elevated mortality risk in this population, this study highlights the potential for poverty alleviation programmes to mitigate mortality rates in one of the highest-risk population subgroups. |
doi_str_mv | 10.1371/journal.pmed.1004486 |
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This cohort study utilised Brazilian administrative datasets, linking social and health system data from the 100 Million Brazilian Cohort, a population-representative study. We followed individuals who applied for BFP following a single hospitalisation with a psychiatric disorder between 2008 and 2015. The outcome was mortality and specific causes, defined according to International Classification of Diseases 10th Revision (ICD-10). Cox proportional hazards models estimated the hazard ratio (HR) for overall mortality and competing risks models estimated the HR for specific causes of death, both associated with being a BFP recipient, adjusted for confounders, and weighted with a propensity score. We included 69,901 psychiatric patients aged between 10 and 120, with the majority being male (60.5%), and 26,556 (37.99%) received BFP following hospitalisation. BFP was associated with reduced overall mortality (HR 0.93, 95% CI 0.87,0.98, p 0.018) and mortality due to natural causes (HR 0.89, 95% CI 0.83, 0.96, p < 0.001). Reduction in suicide (HR 0.90, 95% CI 0.68, 1.21, p = 0.514) was observed, although it was not statistically significant. The BFP's effects on overall mortality were more pronounced in females and younger individuals. In addition, 4% of deaths could have been prevented if BFP had been present (population attributable risk (PAF) = 4%, 95% CI 0.06, 7.10).
BFP appears to reduce mortality rates among psychiatric patients. While not designed to address elevated mortality risk in this population, this study highlights the potential for poverty alleviation programmes to mitigate mortality rates in one of the highest-risk population subgroups.</description><identifier>ISSN: 1549-1676</identifier><identifier>ISSN: 1549-1277</identifier><identifier>EISSN: 1549-1676</identifier><identifier>DOI: 10.1371/journal.pmed.1004486</identifier><identifier>PMID: 39621791</identifier><language>eng</language><publisher>United States: Public Library of Science</publisher><subject>Adolescent ; Adult ; Aged ; Aged, 80 and over ; Analysis ; Biology and Life Sciences ; Brazil - epidemiology ; Cause of Death ; Child ; Cohort Studies ; Ecology and Environmental Sciences ; Female ; Health aspects ; Hospitalization - economics ; Humans ; Male ; Medical research ; Medicine and Health Sciences ; Medicine, Experimental ; Mental Disorders - economics ; Mental Disorders - mortality ; Mental illness ; Middle Aged ; People and places ; Prevention ; Proportional Hazards Models ; Suicide ; Young Adult</subject><ispartof>PLoS medicine, 2024-12, Vol.21 (12), p.e1004486</ispartof><rights>Copyright: © 2024 Bonfim et al. This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.</rights><rights>COPYRIGHT 2024 Public Library of Science</rights><rights>2024 Bonfim et al 2024 Bonfim et al</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><cites>FETCH-LOGICAL-c488t-ce4089c405792b202a264d06256d41adb1526f1d9d680e7509f14b15ab636b1b3</cites><orcidid>0000-0003-2959-4650 ; 0000-0001-6777-0104 ; 0000-0003-1066-8584 ; 0000-0001-8361-6721</orcidid></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC11649113/pdf/$$EPDF$$P50$$Gpubmedcentral$$Hfree_for_read</linktopdf><linktohtml>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC11649113/$$EHTML$$P50$$Gpubmedcentral$$Hfree_for_read</linktohtml><link.rule.ids>230,314,723,776,780,881,27903,27904,36992,53770,53772</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/39621791$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><contributor>Hanlon, Charlotte</contributor><creatorcontrib>Bonfim, Camila</creatorcontrib><creatorcontrib>Alves, Flávia</creatorcontrib><creatorcontrib>Fialho, Érika</creatorcontrib><creatorcontrib>Naslund, John A</creatorcontrib><creatorcontrib>Barreto, Maurício L</creatorcontrib><creatorcontrib>Patel, Vikram</creatorcontrib><creatorcontrib>Machado, Daiane Borges</creatorcontrib><title>Conditional cash transfers and mortality in people hospitalised with psychiatric disorders: A cohort study of the Brazilian Bolsa Família Programme</title><title>PLoS medicine</title><addtitle>PLoS Med</addtitle><description>Psychiatric patients experience lower life expectancy compared to the general population. Conditional cash transfer programmes (CCTPs) have shown promise in reducing mortality rates, but their impact on psychiatric patients has been unclear. This study tests the association between being a Brazilian Bolsa Família Programme (BFP) recipient and the risk of mortality among people previously hospitalised with any psychiatric disorders.
This cohort study utilised Brazilian administrative datasets, linking social and health system data from the 100 Million Brazilian Cohort, a population-representative study. We followed individuals who applied for BFP following a single hospitalisation with a psychiatric disorder between 2008 and 2015. The outcome was mortality and specific causes, defined according to International Classification of Diseases 10th Revision (ICD-10). Cox proportional hazards models estimated the hazard ratio (HR) for overall mortality and competing risks models estimated the HR for specific causes of death, both associated with being a BFP recipient, adjusted for confounders, and weighted with a propensity score. We included 69,901 psychiatric patients aged between 10 and 120, with the majority being male (60.5%), and 26,556 (37.99%) received BFP following hospitalisation. BFP was associated with reduced overall mortality (HR 0.93, 95% CI 0.87,0.98, p 0.018) and mortality due to natural causes (HR 0.89, 95% CI 0.83, 0.96, p < 0.001). Reduction in suicide (HR 0.90, 95% CI 0.68, 1.21, p = 0.514) was observed, although it was not statistically significant. The BFP's effects on overall mortality were more pronounced in females and younger individuals. In addition, 4% of deaths could have been prevented if BFP had been present (population attributable risk (PAF) = 4%, 95% CI 0.06, 7.10).
BFP appears to reduce mortality rates among psychiatric patients. While not designed to address elevated mortality risk in this population, this study highlights the potential for poverty alleviation programmes to mitigate mortality rates in one of the highest-risk population subgroups.</description><subject>Adolescent</subject><subject>Adult</subject><subject>Aged</subject><subject>Aged, 80 and over</subject><subject>Analysis</subject><subject>Biology and Life Sciences</subject><subject>Brazil - epidemiology</subject><subject>Cause of Death</subject><subject>Child</subject><subject>Cohort Studies</subject><subject>Ecology and Environmental Sciences</subject><subject>Female</subject><subject>Health aspects</subject><subject>Hospitalization - economics</subject><subject>Humans</subject><subject>Male</subject><subject>Medical research</subject><subject>Medicine and Health Sciences</subject><subject>Medicine, Experimental</subject><subject>Mental Disorders - economics</subject><subject>Mental Disorders - mortality</subject><subject>Mental illness</subject><subject>Middle Aged</subject><subject>People and places</subject><subject>Prevention</subject><subject>Proportional Hazards Models</subject><subject>Suicide</subject><subject>Young Adult</subject><issn>1549-1676</issn><issn>1549-1277</issn><issn>1549-1676</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2024</creationdate><recordtype>article</recordtype><sourceid>DOA</sourceid><recordid>eNqNkk-O0zAUhyMEYoaBGyBkiQ0sWuzEcWM2qFMxUGmkQfzbWi-2k7hK7IztAOUcXINTcDFcWkZTiQUrxy_f--y8_LLsMcFzUizIi42bvIV-Pg5azQnGlFbsTnZKSspnhC3Y3VvPJ9mDEDYY5xxzfD87KTjLyYKT0-zHylllonFJhSSEDkUPNjTaBwRWocH5CL2JW2QsGrUbe406F0azqwat0FcTOzSGrewMRG8kUiY4r1L_S7RE0nVJgEKc1Ba5BsVOo3MP301vwKJz1wdAFzD8-pn26J13rYdh0A-zew30QT86rGfZp4vXH1dvZ5dXb9ar5eVM0qqKM6kprrikuFzwvM5xDjmjCrO8ZIoSUDUpc9YQxRWrsF6UmDeEpiLUrGA1qYuzbL33KgcbMXozgN8KB0b8KTjfCvDRyF4LrRhmjWoqzoDWFUmauqxxvvOVNePJ9WrvGqc6_RGpbRpkfyQ9fmNNJ1r3RRDCKCekSIZnB4N315MOUQwmSN33YLWbgigIxTynhJOEPt2jLaS7Gdu4pJQ7XCyrvCjSt1Y4UbN_UK22Op3vrG5MKh_xz4946WzU32ILUwhi_eH9_7NXn49ZumeldyF43dxMhWCxy7I4ZFnssiwOWU5tT25P9Kbpb3iL3xWi9AI</recordid><startdate>20241202</startdate><enddate>20241202</enddate><creator>Bonfim, Camila</creator><creator>Alves, Flávia</creator><creator>Fialho, Érika</creator><creator>Naslund, John A</creator><creator>Barreto, Maurício L</creator><creator>Patel, Vikram</creator><creator>Machado, Daiane Borges</creator><general>Public Library of Science</general><general>Public Library of Science (PLoS)</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>IOV</scope><scope>ISR</scope><scope>7X8</scope><scope>5PM</scope><scope>DOA</scope><orcidid>https://orcid.org/0000-0003-2959-4650</orcidid><orcidid>https://orcid.org/0000-0001-6777-0104</orcidid><orcidid>https://orcid.org/0000-0003-1066-8584</orcidid><orcidid>https://orcid.org/0000-0001-8361-6721</orcidid></search><sort><creationdate>20241202</creationdate><title>Conditional cash transfers and mortality in people hospitalised with psychiatric disorders: A cohort study of the Brazilian Bolsa Família Programme</title><author>Bonfim, Camila ; Alves, Flávia ; Fialho, Érika ; Naslund, John A ; Barreto, Maurício L ; Patel, Vikram ; Machado, Daiane Borges</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c488t-ce4089c405792b202a264d06256d41adb1526f1d9d680e7509f14b15ab636b1b3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2024</creationdate><topic>Adolescent</topic><topic>Adult</topic><topic>Aged</topic><topic>Aged, 80 and over</topic><topic>Analysis</topic><topic>Biology and Life Sciences</topic><topic>Brazil - epidemiology</topic><topic>Cause of Death</topic><topic>Child</topic><topic>Cohort Studies</topic><topic>Ecology and Environmental Sciences</topic><topic>Female</topic><topic>Health aspects</topic><topic>Hospitalization - economics</topic><topic>Humans</topic><topic>Male</topic><topic>Medical research</topic><topic>Medicine and Health Sciences</topic><topic>Medicine, Experimental</topic><topic>Mental Disorders - economics</topic><topic>Mental Disorders - mortality</topic><topic>Mental illness</topic><topic>Middle Aged</topic><topic>People and places</topic><topic>Prevention</topic><topic>Proportional Hazards Models</topic><topic>Suicide</topic><topic>Young Adult</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Bonfim, Camila</creatorcontrib><creatorcontrib>Alves, Flávia</creatorcontrib><creatorcontrib>Fialho, Érika</creatorcontrib><creatorcontrib>Naslund, John A</creatorcontrib><creatorcontrib>Barreto, Maurício L</creatorcontrib><creatorcontrib>Patel, Vikram</creatorcontrib><creatorcontrib>Machado, Daiane Borges</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>Gale in Context : Opposing Viewpoints</collection><collection>Science (Gale in Context)</collection><collection>MEDLINE - Academic</collection><collection>PubMed Central (Full Participant titles)</collection><collection>DOAJ, Directory of Open Access Journals</collection><jtitle>PLoS medicine</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Bonfim, Camila</au><au>Alves, Flávia</au><au>Fialho, Érika</au><au>Naslund, John A</au><au>Barreto, Maurício L</au><au>Patel, Vikram</au><au>Machado, Daiane Borges</au><au>Hanlon, Charlotte</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Conditional cash transfers and mortality in people hospitalised with psychiatric disorders: A cohort study of the Brazilian Bolsa Família Programme</atitle><jtitle>PLoS medicine</jtitle><addtitle>PLoS Med</addtitle><date>2024-12-02</date><risdate>2024</risdate><volume>21</volume><issue>12</issue><spage>e1004486</spage><pages>e1004486-</pages><issn>1549-1676</issn><issn>1549-1277</issn><eissn>1549-1676</eissn><abstract>Psychiatric patients experience lower life expectancy compared to the general population. Conditional cash transfer programmes (CCTPs) have shown promise in reducing mortality rates, but their impact on psychiatric patients has been unclear. This study tests the association between being a Brazilian Bolsa Família Programme (BFP) recipient and the risk of mortality among people previously hospitalised with any psychiatric disorders.
This cohort study utilised Brazilian administrative datasets, linking social and health system data from the 100 Million Brazilian Cohort, a population-representative study. We followed individuals who applied for BFP following a single hospitalisation with a psychiatric disorder between 2008 and 2015. The outcome was mortality and specific causes, defined according to International Classification of Diseases 10th Revision (ICD-10). Cox proportional hazards models estimated the hazard ratio (HR) for overall mortality and competing risks models estimated the HR for specific causes of death, both associated with being a BFP recipient, adjusted for confounders, and weighted with a propensity score. We included 69,901 psychiatric patients aged between 10 and 120, with the majority being male (60.5%), and 26,556 (37.99%) received BFP following hospitalisation. BFP was associated with reduced overall mortality (HR 0.93, 95% CI 0.87,0.98, p 0.018) and mortality due to natural causes (HR 0.89, 95% CI 0.83, 0.96, p < 0.001). Reduction in suicide (HR 0.90, 95% CI 0.68, 1.21, p = 0.514) was observed, although it was not statistically significant. The BFP's effects on overall mortality were more pronounced in females and younger individuals. In addition, 4% of deaths could have been prevented if BFP had been present (population attributable risk (PAF) = 4%, 95% CI 0.06, 7.10).
BFP appears to reduce mortality rates among psychiatric patients. While not designed to address elevated mortality risk in this population, this study highlights the potential for poverty alleviation programmes to mitigate mortality rates in one of the highest-risk population subgroups.</abstract><cop>United States</cop><pub>Public Library of Science</pub><pmid>39621791</pmid><doi>10.1371/journal.pmed.1004486</doi><orcidid>https://orcid.org/0000-0003-2959-4650</orcidid><orcidid>https://orcid.org/0000-0001-6777-0104</orcidid><orcidid>https://orcid.org/0000-0003-1066-8584</orcidid><orcidid>https://orcid.org/0000-0001-8361-6721</orcidid><oa>free_for_read</oa></addata></record> |
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subjects | Adolescent Adult Aged Aged, 80 and over Analysis Biology and Life Sciences Brazil - epidemiology Cause of Death Child Cohort Studies Ecology and Environmental Sciences Female Health aspects Hospitalization - economics Humans Male Medical research Medicine and Health Sciences Medicine, Experimental Mental Disorders - economics Mental Disorders - mortality Mental illness Middle Aged People and places Prevention Proportional Hazards Models Suicide Young Adult |
title | Conditional cash transfers and mortality in people hospitalised with psychiatric disorders: A cohort study of the Brazilian Bolsa Família Programme |
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